目的 研究龙须草Juncus setchuensis茎髓中的菲类化学成分。方法 采用多种柱色谱方法分离纯化, 通过理化性质及波谱分析技术鉴定化合物的结构。结果 从龙须草茎髓的乙醇提取物中分离得到5个菲类化合物, 分别鉴定为8-羟甲基-2-羟基-1-甲基-5-乙烯基-9,10-二氢菲(1)、4-ethenyl-9,10-dihydro-1,8-dimethyl-2,7-phenanthrenediol(2)、厄弗酚(3)、去氢厄弗酚(4)、4-ethenyl-9,10-dihydro-7-hydroxy-8-methyl-1-phenanthrenecarboxylic acid(5)。结论 化合物1为未见文献报道的具有二氢菲类结构母核的新化合物, 命名为龙须草醇A。

Objective To study the phenanthrenes from the pith of Juncus setchuensis. Methods The compounds were separated and purified by column chromatographies amd their structures were elucidated by physicochemical properties and spectroscopic methods. Results Five compounds were isolated from the 95% ethanol extract from the pith of J. setchuensis, their structures were determined as 8-hydroxymethyl-2-hydroxy-1-methyl-5-vinyl-9,10-dihydrophenanthrene (1), 4-ethenyl-9,10-dihydro-1,8-dimethyl-2,7-phenan-threnediol (2), effusol (3), dehydroeffusol (4), and 4-ethenyl-9,10-dihydro-7-hydroxy-8-methyl-1-phenanthrenecarboxylic acid (5). Conclusion Compound 1 is a new compound without literature report, named 8-hydroxymethyl-2-hydroxy-1-methyl-5-vinyl-9,10-dihydrophenanthrene.

中国博士后科学基金面上资助项目(2015M570257)