[关键词]
[摘要]
随着中药总黄酮提取物药效认可度的提高,其中所含的碳苷黄酮越来越多的被研究者们发现,碳苷黄酮在保护心血管疾病方面的作用日益显现.综述了近年来分离鉴定的碳苷黄酮及其抗氧化、保护心肌缺血损伤等药理活性,以及抗心肌缺血的可能作用机制,以期为碳苷黄酮的研究和开发提供信息和依据.
[Key word]
[Abstract]
With the improvement of the public's recognition to the efficacy of total flavonoid extract from Chinese materia medica, wherein the C-glycosylflavones contained have been found by more and more researchers. The role of C-glycosylflavones to protect the cardiovascular disease is becoming more evident. The recent isolation and identification of C-glycosylflavones with the pharmacological activity about anti-oxidant and protecting myocardial ischemia injury and the possible mechanisms of anti-myocardial ischemia are reviewed in this article, so as to provide the information and evidence for the further research and development of C-glycosylflavones.
[中图分类号]
[基金项目]
国家自然科学基金资助项目(81473313);教育部高等学校博士学科点专项科研基金(博导类)(20133237110010);江苏省2013年度普通高校研究生科研创新计划项目(CXZZ13_0630);江苏省高校中药资源产业化过程协同创新中心建设专项(2013);江苏高校优势学科建设工程资助项目;国家公益性行业专项(201407002);国家公共卫生行业专项(2014002)