目的 研究小花金挖耳Carpesium minum地上部分的化学成分.方法 采用硅胶柱色谱及重结晶等方法进行分离纯化,利用波谱数据和X-ray单晶衍射鉴定结构.结果 从小花金挖耳地上部分95%乙醇提取物的醋酸乙酯萃取部位中分离得到1个新化合物,鉴定为4β-乙酰氧基-伪愈创木烷-11(13)-烯-12, 8α-内酯,其相对构型由X-ray单晶衍射确定.结论 该化合物为新化合物,命名为小花金挖耳素,属于伪愈创木烷类倍半萜内酯.

Objective To study the chemical constituents in the ethanol extract from aerial part of Carpesium minum. Methods Repeated column chromatography with silical gel and recrystallization were used to isolate the chemical constituents. The structure was elucidated on spectroscopy and X-ray diffraction. Results A new compound was isolated and identified as 4β-acetoxy-11 (13)- pseudoguaien-12, 8α-olide. Conclusion This compound is a new compound, named carpeminin, which belongs to pseudoguaianolide sesquiterpenes.

重庆市教委科技项目(KJ100719)