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[摘要]
目的 对福建野鸦椿Euscaphis fukienensis籽的化学成分进行分离与鉴定。方法 采用硅胶柱色谱、Sephadex LH-20柱色谱、重结晶等方法进行分离纯化,根据理化性质和波谱数据鉴定化合物结构。结果 从福建野鸦椿籽70%乙醇提取物中分离得到10个化合物,其中8个为酚酸类成分,分别鉴定为邻苯二甲酸-双 (2'-乙基庚基)酯(1)、琥珀酸(2)、没食子酸(3)、异鼠李素-3-O-葡萄糖苷(4)、对羟基苯甲酸(5)、2-甲基-5,7-二羟基色原酮(6)、己二烯二酸(7)、槲皮素-3-O-葡萄糖苷(8)、β-谷甾醇(9)、胡萝卜苷(10)。结论 化合物1~7均为首次从该植物中分离得到。
[Key word]
[Abstract]
Objective To investigate the compouds from methylene dichloride and n-butyl alcohol parts of 70% ethanol extract of the fruits of Euscaphis fukienensis. Methods The compounds were isolated and purified by Sephadex LH-20, silica gel column chromatographies, and recrystallization. Their structures were identified by physicochemical properties and spectroscopic methods. Results Ten compounds were isolated and identified as 1, 2-benzenedicarboxylic acid (1), butanedioic acid (2), gallic acid (3), isorhamnetin-3-O-glucoside (4), 4-hydroxy-benzoic acid (5), 2-methyl-5, 7-dihydroxychrom one (6), muconic acid (7), quercetin-3-O- glycosidase (8), β-sitosterol (9), and daucostrol (10). Conclusion Compounds 1—7 are isolated from the fruits of E. fukienensis for the first time.
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[基金项目]
湖南省“十二五”重点学科中药学资助;湖南中医药大学“十二五”校级重点学科药物分析学资助;湖南省高层次卫生人才“225”工程项目资助