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[摘要]
目的 研究酸枣仁Ziziphi Spinosae Semen的化学成分。方法 采用D-101大孔吸附树脂、硅胶、ODS、Sephadex LH-20和Toyopearl HW-40等色谱分离手段进行分离纯化,根据化合物的理化性质和波谱数据鉴定化合物的结构。结果 从酸枣仁70%乙醇提取物中分离得到了5个化合物,分别鉴定为6",6'''-二阿魏酰异斯皮诺素(1)、山柰酚-3-O-β-D-吡喃木糖基-(1→2)- [α-L-吡喃鼠李糖基-(1→6)]-β-D-吡喃葡萄糖苷(2)、斯皮诺素(3)、异斯皮诺素(4)、6'''-阿魏酰斯皮诺素(5)。结论 化合物1为1个新的黄酮碳苷类化合物,命名为6",6'''-二阿魏酰异斯皮诺素。化合物2为首次从该属植物中分离得到。
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[Abstract]
Objective To study the chemical constituents from 70% ethanol extract of Ziziphi Spinosae Semen. Methods Five compounds were isolated and purified by macroporous resin D101, silica gel, Sephadex LH-20, Toyopearl HW-40, and ODS column chromatographies. Results Five compounds (1—5) were isolated from 70% ethanol extract of Ziziphi Spinosae Semen. Their structures were identified by spectroscopic methods, as 6", 6'''-diferuloylisospinosin (1), kaempferol-3-O-β-D-xylopyranosyl-(1→2)- [α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside (2), spinosin (3), isospinosin (4), and 6'''-feruloylspinosin (5). Conclusion Compound 1 is a new flavone C-glycoside named 6", 6'''-diferuloylisospinosin. Compound 2 is reported from the genus Ziziphus Mill. for the first time.
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