目的 对宽叶兔儿风Ainsliaea latifolia全草的化学成分进行研究。方法 采用硅胶柱色谱、凝胶柱色谱、中压制备液相、高压制备液相等方法进行分离纯化，通过核磁共振、质谱等波谱手段对化合物进行结构鉴定。结果 从宽叶兔儿风80%乙醇提取物中分离得到13个化合物，分别鉴定为木栓酮（1）、蒲公英萜醇乙酸酯（2）、3β-hydroxy-11α，12α-epoxy- friedoolean-14-ene（3）、careborin（4）、cis-careborin（5）、3α-E-feruloyltaraxerol（6）、3α-Z-feruloyltaraxerol（7）、3-oxo-11α- methoxyolean-12-ene（8）、diaspanolide A（9）、diaspanolide B（10）、ainsliaolide A（11）、豆甾醇（12）、β-谷甾醇（13）。结论 13个化合物中包括8个三萜类化合物（1～8），3个倍半萜类化合物（9～11），2个甾体类化合物（12～13）。化合物1～13均为首次从该植物中分离得到。

Objective To isolate and identify the chemical constituents of Ainsliaea latifolia. Methods Compounds were isolated by various kinds of column chromatographies on silica gel, Sephadex LH-20, MPLC, and HPLC, and their structures were elucidated by the physicochemical properties and spectral analyses. Results Thirteen chemical constituents were obtained and identified as friedelin (1), taraxeryl acetate (2), 3β-hydroxy-11α, 12α-epoxy-friedoolean-14-ene (3), careborin (4), cis-careborin (5), 3α-E-feruloyltaraxerol (6), 3α-Z-feruloyltaraxerol (7), 3-oxo-11α-methoxyolean-12-ene (8), diaspanolide A (9), diaspanolide B (10), ainsliaolide A (11), stigmasterol (12), and β-sitosterol (13). Conclusion Among the isolated 13 compounds, there are 8 triterpenoids (1—8), 3 sesquiterpenoids (9—11), and 2 steroidals (12—13). All the compounds are isolated from A. latifolia for the first time.