目的 研究畲药紫玉兰Magnolia liliflora花蕾的化学成分。方法 利用硅胶色谱和Sephadex LH-20等色谱方法进行分离纯化，根据化合物的理化性质及谱学数据鉴定化合物的结构。结果 从紫玉兰干燥花蕾的甲醇提取物中分离得到7个化合物，分别鉴定为单木质醇葡萄糖苷（1）、(1S, 3R)-1-(3, 4-二甲氧基-苯基)-2-[4-(3-羟基-丙基)-2-甲氧基-苯氧基]-丙烷-1, 3-二醇（2）、3′, 4-O-二甲基雪松素（3）、4-O-甲基雪松素（4）、β-胡萝卜苷（5）、β-谷甾醇（6）和山柰酚-3-O-(6″-反式-对-香豆酰基)-α-D-甘露吡喃糖苷（7）。结论 以上化合物均首次从紫玉兰中分离得到，其中化合物3、4、7为首次从木兰属植物中分离得到，化合物1首次从天然产物中分离得到，并首次报道其完整¹³C-NMR数据。

Objective To study the chemical constituents from the flower buds of She Medicine Magnolia liliflora. Methods The compounds were isolated and purified by chromatography on silica gel and Sephadex LH-20 columns. Their structures were elucidated by the physicochemical and spectroscopic evidences. Results Seven compounds were isolated from the methanol extracts in the flower buds of M. liliflora and were identified as monolignol glucosides (1), (1S, 3R)-1-(3, 4-dimethoxy-phenyl)-2-[4-(3- hydroxy-propyl)-2-methoxy-phenoxy]-propane-1, 3-diol (2), 3′, 4-O-dimetbylcedrusin (3), 4-O-metbylcedrusin (4), β-daucosterol (5), β-sitosterol (6), and kaempferol-3-O-(6″-trans-p-coumaroyl)-α-D-mannosepyran-glucoside (7). Conclusion All of these compounds are isolated from the flower buds of M. liliflora for the first time. Compounds 3, 4, and 7 are first isolated from the plants in Magnolia L. Compound 1 is isolated from the natural products for the first time, and the ¹³C-NMR data of compound 1 are expounded for the first time.

国家自然科学基金资助项目（31200260）；北京市教委科技成果转化与产业化项目（2008）；中央民族大学“111引智工程”资助项目（B08044）；中央民族大学“985”工程资助项目（MUC985-9）；中央民族大学大学生创新创业训练计划资助项目（BEIJ20131100004）