目的研究疏刺茄Solanum nienkui的化学成分。方法应用硅胶柱色谱、Sephadex LH-20柱色谱、反相柱色谱及重结晶等方法分离纯化,根据理化性质和光谱数据鉴定化合物结构。结果从疏刺茄的三氯甲烷部位分离得到11个化合物,分别鉴定为7,2′,4′-三羟基-5-甲氧基异黄酮(1)、香叶木素(2)、柚皮素(3)、山柰酚(4)、槲皮素(5)、咖啡酸乙酯(6)、原儿茶醛(7)、邻羟基苯甲酸(8)、香草醛(9)、水杨酸甲酯(10)、N-p-香豆酰酪胺(11)。结论所有化合物均为首次从该植物中分离得到,化合物1为首次从茄科植物中分离得到。

Objective To study the chemical constituents from Solanum nienkui. Methods The compounds were isolated by chromatography on silica gel, Sephadex LH-20, and reverse phase column as well as recrystallisation, and their structures were identified on the basis of physicochemical characteristics and spectroscopic analyses.Results Eleven compounds were obtained from the CHCl 3 extract of S. nienkui with the structures as 7, 2′, 4′-trihydroxys-5-methoxyisoflavanone(1), diosmetin(2), naringenin (3), kaempferol(4), quercetin(5), ethyl caffeate (6), protocatechuic aldehyde(7), o-hydroxybenzoic acid(8), vanillin (9), methylsalicylate (10), and N-p-paprazine (11). ConclusionAll the compounds are isolated from this plant for the first time, and compound 1 is isolated from the plants in Solanaceae for the first time.

教育部新世纪优秀人才支持计划(NCET-08-0656);海南省重大科技项目(ZDZX20100005)