目的 研究椿皮的化学成分。方法 采用硅胶、凝胶、ODS及RP-HPLC对椿皮化学成分进行分离纯化，并根据理化性质和波谱数据鉴定化合物的结构。结果 从椿皮95%乙醇提取物中分离得到12个化合物，分别鉴定为erythro- guaiacylglycerol-β-O-4′-coniferyl ether（1）、threo-guaiacylglycerol-β-O-4′-sinapyl ether（2）、threo-guaiacylglycerol-β-O-4′- dihydroconiferyl ether（3）、咖啡酸甲酯（4）、松柏苷（5）、scopoletin（6）、7-methoxy-2H-chromene（7）、香草醛（8）、4-hydroxy-2(E)-nonenoic acid（9）、(9S, 12S, 13S)-(E)-9, 12, 13-trihydroxy-10-octadecaenoic acid（10）、β-谷甾醇（11）和胡萝卜苷（12）。结论 化合物1～5、7、9和10为首次从该属植物中分离得到。

Objective To investigate the chemical constituents in the barks of Ailanthus altissima. Methods The chemical consituents were isolated by silica gel, Sephadex LH-20, ODS, as well as RP-HPLC column chromatographies. Their structures were identified on the basis of physicochemical properties and spectral analysis. Results Twelve compounds were isolated and idenified as erythro-guaiacylglycerol-β-O-4′-coniferyl ether (1), threo-guaiacylglycerol-β-O-4′-sinapyl ether (2), threo-guaiacylglycerol-β-O-4′- dihydroconiferyl ether (3), caffeic acid methyl ester (4), coniferin (5), scopoletin (6), 7-methoxy-2H-chromene (7), vanillin (8), 4-hydroxy-2(E)-nonenoic acid (9), (9S, 12S, 13S)-(E)-9, 12, 13-trihydroxy-10-octadecaenoic acid (10), β-sitosterol (11), and daucosterol (12), respectively. Conclusion Compounds 1—5, 7, 9, and 10 are isolated from this plant for the first time.

教育部长江学者创新团队项目（IRT0965）；广东省自然科学基金团队项目（8351063201000003）