目的: 研究尾叶香茶菜Rabdosia excisa的化学成分。方法: 利用硅胶柱色谱法进行分离和纯化, 通过理化性质和波谱数据鉴定化合物结构。结果: 从尾叶香茶菜中分离鉴定了15个化合物, 分别为山香三萜二烯酸(1)、α-香树脂醇棕榈酸酯(2)、豆甾醇(3)、β-谷甾醇(4)、棕榈酸(5)、熊果酸(6)、1α,6,11β,15β-四乙酰基-6,7-断裂-7,20-内酯-对映-贝壳杉-16-烯(7)、2α,3α-二羟基乌苏-12-烯-28-酸(8)、马斯里酸(9)、2α,3α,19-三羟基-12-烯-28-乌索酸(10)、毛叶香茶菜素E(11)、6β,11α,15α-三羟基-6,7断裂-6,20-环氧2-1α,7-内酯-对映-贝壳杉-16-烯(12)、对映-7α,20-环氧-贝壳杉烷-16-烯-1α,6β,7β,14β,15β-五醇-1-O-葡萄吡喃糖苷(13)、冬凌草甲素(14)、胡萝卜苷(15)。结论除了化合物3、5、6、14、15外, 其余化合物均为首次从尾叶香茶菜中发现。

Objective: To research the chemical constituents of Rabdosia excisa. Methods: Compounds were separated and purified by silica gel column chromatography and their structures were determined by spectroscopic method. Results: Fifteen compounds isolated from the leaves of this plant were identified as: hyptadienic acid (1), α-amyrin palmitate (2), stigmasterol (3), β-sitosterol (4),palmitic acid (5), ursolic acid (6), 1α, 6, 11β, 15β-tetraacetoy-6, 7-seco-7, 20-olide-ent-kaur-16-en (7), 2α, 3α-dihydroxy-urs-12-en-28-oic acid (8), maslinic acid (9), 2α, 3α, 19-trihydroxy-urs-12-en-28-oic acid (10), maoyecrystal E (11); 6β, 11α, 15α-trihydroxy-6, 7-seco-6, 20-epoxy-1α, 7-olide-ent-kaur-6-en, epinodosinol (12), enmenol-glucoside (13), oridonol (14), and daucosterol(15). Conclusion: All the constituents are found in R. excisa for the first time except constituents 3, 5, 6, 14, and 15.

河南省基础与前沿技术研究计划项目(102300410006)