目的 研究雪松Cedrus deodara松针中黄酮类化学成分。方法 采用硅胶、Sephadex LH-20等柱色谱方法对其醋酸乙酯萃取部位中黄酮类化学成分进行分离和纯化,并根据其理化性质及波谱数据鉴定结构。结果 从雪松松针中分离得到5个黄酮类化合物,分别鉴定为3′,5′-二甲氧基杨梅素-3-O-(6″-O-乙酰基)-α-D-吡喃葡萄糖苷[3′,5′-dimethoxymyricetin-3-O-(6′′-O-acetyl)-α-D-glucopyranoside,1]、杨梅素(myricetin,2)、2R,3R-二氢杨梅素(2R,3R-dihydromyricetin,3)、槲皮素(quercetin,4)、2R,3R-二氢槲皮素(2R,3R-dihydroquercetin,5)。结论 化合物1为新化合物,命名为雪松酮A(cedrusone A),化合物2～5均为首次从该属植物针叶中分离得到。

Objective To study the chemical constituents of flavonoids in the pine needles of Cedrus deodara. Methods Flavonoids were isolated and purified from ethyl acetate extract of the pine needles by chromatography on silica gel and Sephadex LH-20. Their structures were identified on the basis of spectroscopic analysis and chemical evidence. Results Five flavonoids were isolated and identified as 3',5'-dimethoxymyricetin-3-O-(6"-O-acetyl)-a-D-glucopyranoside(1), myricetin (2),2R,3R-dihydromyricetin(3), quercetin (4), and 2R,3R-dihydroquercetin (5). Conclusion Compound 1 is a new compound named as cedrusone A. Compounds 2-5 are isolated from the pine needles in the plants of Cedrus Trew for the first time.

甘肃省技术研究与专项计划项目(0709TCYA022);甘肃省卫生厅科研计划项目(WST07-02)