目的 研究中华补血草Limonium sinense全草的化学成分。方法 利用萃取、制备薄层、反复硅胶、Sephadex LH-20、开放ODS柱色谱等方法进行分离纯化,根据理化常数测定及波谱分析对分离得到的化合物进行结构鉴定。结果 分离得到11个化合物,分别鉴定为异鼠李素(1)、甘露醇(2)、β-谷甾醇(3)、齐墩果酸(4)、槲皮素(5)、槲皮素3-O-β-D-葡萄糖苷(6)、没食子酸乙酯(7)、山柰酚(8)、山柰酚-3-O-α-L-吡喃鼠李糖苷(9)、(+)-儿茶素(10)、异鼠李素-3-芸香糖苷(11)。结论 化合物4、6、7、10、11为首次从中华补血草中分离得到。

Objective To study the chemical constituents of Limonium sinense.Methods Eleven compounds were isolated by extraction,preparation-TLC,repeat-silicagel column,Sephadex-LH20,and opened-ODS column chromatography,and identified on the basis of physicochemical constant and spectra analysis.Results Eleven compounds were isolated and their structures were identified as isorhamnetin(1),mannitol(2),β-sitosterol(3),oleanolic acid(4),quercetin(5),quercetin-3-O-β-D-glucoside(6),ethylgallate(7),kaempferol(8),kaempferol-3-O-α-L-rhamnopyranoside(9),(+)-catechin(10),and isorhamnetin-3-rutinoside(11).Conclusion Compounds 4,6,7,10,and 11 are obtained from L.sinense for the first time.

江苏省滩涂生物资源与环境保护重点建设实验室资助项目(JLCBE09025);江苏省盐城师范学院引进人才科研启动基金项目(YCTURS06017)