[关键词]
[摘要]
目的 研究中华补血草Limonium sinense全草的化学成分。方法 利用萃取、制备薄层、反复硅胶、Sephadex LH-20、开放ODS柱色谱等方法进行分离纯化,根据理化常数测定及波谱分析对分离得到的化合物进行结构鉴定。结果 分离得到11个化合物,分别鉴定为异鼠李素(1)、甘露醇(2)、β-谷甾醇(3)、齐墩果酸(4)、槲皮素(5)、槲皮素3-O-β-D-葡萄糖苷(6)、没食子酸乙酯(7)、山柰酚(8)、山柰酚-3-O-α-L-吡喃鼠李糖苷(9)、(+)-儿茶素(10)、异鼠李素-3-芸香糖苷(11)。结论 化合物4、6、7、10、11为首次从中华补血草中分离得到。
[Key word]
[Abstract]
Objective To study the chemical constituents of Limonium sinense. Methods Eleven compounds were isolated by extraction, preparation-TLC, repeat-silicagel column, Sephadex-LH20, and opened-ODS column chromatography, and identified on the basis of physicochemical constant and spectra analysis. Results Eleven compounds were isolated and their structures were identified as isorhamnetin (1), mannitol (2), β-sitosterol (3), oleanolic acid (4), quercetin (5), quercetin-3-O-β-D-glucoside (6), ethylgallate (7), kaempferol (8), kaempferol-3-O-α-L-rhamnopyranoside (9), (+)-catechin (10), and isorhamnetin-3-rutinoside (11). Conclusion Compounds 4, 6, 7, 10, and 11 are obtained from L. sinense for the first time.
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[基金项目]
江苏省滩涂生物资源与环境保护重点建设实验室资助项目(JLCBE09025);江苏省盐城师范学院引进人才科研启动基金项目(YCTURS06017)