[关键词]
[摘要]
目的研究野拔子的化学成分。方法用硅胶、凝胶柱色谱等方法分离化合物,用波谱方法鉴定其结构。结果从野拔子脂溶性部位中分离鉴定了12个化合物,利用核磁和质谱等光谱数据分析确定其分别为:4',5-二羟基-7-甲氧基黄酮(Ⅰ)、5-羟基-4',6,7-三甲氧基黄酮(Ⅱ)、5,6-二羟基-3',4',7,8-四甲氧基黄酮(Ⅲ)、芹菜素(Ⅳ)、山柰酚(Ⅴ)、槲皮素(Ⅵ)、1H-吲哚-3-羧酸(Ⅶ)、熊果酸(Ⅷ)、齐墩果酸(Ⅸ)、麦角甾-7-烯-3β-醇(Ⅹ)、β-谷甾醇(Ⅺ)和β-胡萝卜苷(Ⅻ)。结论化合物Ⅰ~Ⅹ为首次从该属植物中分离得到。
[Key word]
[Abstract]
Objective To study the chemical constituents from Elsholtzia rugulosa.Methods The compounds were isolated by column chromatography on silica gel,Sephadex LH-20,and MCI-gel CHP-20P.The structures were identified by means of NMR and MS analyses.Results Twelve compounds were isolated and their structures were identified as 4',5-dihydroxy-7-methoxyflavone(Ⅰ),5-hydroxy-4',6,7-trimethoxyflavone(Ⅱ),5,6-dihydroxy-3',4',7,8-tetramethoxyflavone(Ⅲ),apigenin(Ⅳ),kaempferol(Ⅴ),quercetin(Ⅵ),1H-indole-3-carboxylic acid(Ⅶ),ursolic acid(Ⅷ),oleanolic acid(Ⅸ),ergosta-7-en-3β-ol(Ⅹ),β-sitosterol(Ⅺ),and β-daucosterol(ⅩⅡ).Conclusion Compounds Ⅰ-Ⅹ are obtained from the Plants of Elsholtzia Willd.for the first time.
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[基金项目]
云南省自然科学基金项目(2006C0045Q);植物化学与西部植物资源持续利用国家重点实验室基金项目(P2004-14)
