目的研究中华卷柏Selaginella sinensis的化学成分。方法利用Diaion HP-20,Toyopearl HW-40,硅胶柱等柱色谱技术进行分离纯化。根据化合物的理化性质和光谱数据鉴定结构。结果分离并鉴定了11个化合物的结构,分别为:β-谷甾醇(Ⅰ)、香荚兰酸(Ⅱ)、(7S,8R)-4,9,9'-三羟基-3,3'-二甲氧基-7,8-二氢苯并呋喃-1'-丙基新木脂素(Ⅲ)、丁香脂素(Ⅳ)、(-)-松脂素(Ⅴ)、松脂酚-4-O-β-D-葡萄糖苷(Ⅵ)、丁香脂素-4,4'-O-二-β-D-葡萄糖苷(Ⅶ)、β-甲基-D-吡喃木糖苷(Ⅷ)、β-甲基-D-吡喃阿拉伯糖苷(Ⅸ)、扁柏双黄酮(Ⅹ)、阿曼托双黄酮(Ⅺ)。结论化合物Ⅱ~Ⅸ均为首次从该植物中分离得到。

Objective To study the chemical constituents from Selaginella sinensis.Methods The compounds were isolated with Diaion HP-20,Toyopearl HW-40,silica gel column chromatography.The structures of these compounds were identified by physicochemical properties and spectral analyses.Results Eleven compounds were isolated from the 70% acetone-extracts and their structures were identified as β-sitosterol(Ⅰ),vanillic acid(Ⅱ),(7S,8R)-4,9,9'-trihydroxy-3,3'-dimethoxy-7,8-dihydrobenzofuran-1'-propylneolignan(Ⅲ),syringaresinol(Ⅳ),(-)-pinoresinol(Ⅴ),pinoresinol-4-Oβ-D-glucopyranoside(Ⅵ),syringaresinol-4,4'-O-di-β-D-glucopyranoside(Ⅶ),β-methylD-xylopyranoside(Ⅷ),β-methyl-D-arabinopyranoside(Ⅸ),hinokiflavone(Ⅹ),and amentoflavone(Ⅺ).Conclusion Compounds Ⅱ-Ⅸ are isolated from this plant for the first time.

河南省高校新世纪优秀人才支持计划(2006HANCET-08)