目的研究土荆皮正丁醇部位的化学成分。方法反复利用色谱方法进行分离纯化,通过波谱分析、化学方法及参照文献鉴定单体成分结构。结果从土荆皮中分离并鉴定了1个新的苯甲酸甲酯阿洛糖苷(pseudolaroside C,Ⅰ)及12个由该植物中首次分得的化合物(Ⅱ~ⅩⅢ),包括莽草酸(Ⅱ)、莽草酸甲酯(Ⅲ)、芒柄花苷(Ⅳ)、毛蕊异黄酮-7-O-β-D-葡萄糖苷(Ⅴ)、2′-羟基柚皮素(Ⅵ)、素馨苷E(Ⅶ)、长寿花糖苷Ⅱ(Ⅷ)、淫羊藿次苷B5(Ⅸ)、blumenolC葡萄糖苷(Ⅹ)、1,2-氧-异丙叉基-O-β-D-吡喃果糖苷(Ⅺ)、β-D-甲基吡喃果糖苷(ⅩⅡ)、β-D-甲基呋喃果糖苷(ⅩⅢ)等。结论化合物Ⅰ为新化合物,命名为土荆皮苷C。化合物Ⅱ~ⅩⅢ为首次自该植物中分离鉴定。

Objective To study the constituents in the n-butanol extract in the bark of Pseudolarix kaempferi. Methods The compounds were isolated by repeated chromatography and their structures were identified on the basis of spectral methods, chemical analysis, and reference to the literature data. Results A new methyl benzoate allopyranoside, pseudolaroside C, together with 14 known compounds (Ⅱ-ⅩⅤ) were isolated from the bark of P. kaempferi for the first time, such as shikimic acid (Ⅱ), methyl shikimate (Ⅲ), ononin (Ⅳ), calycosin-7-O-β-D-glucopyranoside (Ⅴ), 2′-hydroxynaringenin (Ⅵ), jasminoside E (Ⅶ), roseoside Ⅱ (Ⅷ), icariside B5 (Ⅸ), blumenol C glucoside (Ⅹ), 1, 2-O-isopropylidene-O-β-D-fructopyranose (Ⅺ), methyl O-β-D-frucopyranoside (ⅩⅡ), and methyl O-β-D-frucofuranoside (ⅩⅢ). Conclusion Compound Ⅰ is a new compound named as pseudolaroside C, compounds Ⅱ-ⅩⅢ are isolated and identified from this plant for the first time.

国家“863”科技项目(2003AA2Z030)