目的 研究二蕊荷莲豆Drymariadiandra的化学成分。方法 采用大孔树脂D-101,硅胶柱色谱和PR-18进行反复分离纯化,通过波谱分析方法鉴定化合物结构。结果 分离并鉴定了2个化合物:6-羧甲基-5,7,4′-三羟基黄酮(Ⅰ)和4[E],8[E]-N-[2-D-羟基-十六烷酰基]-1-O-D-吡喃葡萄糖基-4,8-二烯-十八鞘氨醇(大豆脑苷Ⅰ,Ⅱ)。结论 化合物Ⅰ为新化合物,化合物Ⅱ首次从该植物中分离得到。

Objective To investigate the chemical costituents from Drymaria diandra. Methods Compounds were separated and purified by repeated column chromatographies on macroporous resin D-101, silica gel, and RP-18. Two compounds were identified by spectral analysis. Results Two com-pounds were isolated from D. diandra. Their structures were identified as 6-carboxymethyl-5, 7, 4′-trihy-droxyflavone (Ⅰ) and 1-O-β-D-glucopyranosyl-(2S, 3R, 4E, 8E)-Z-N-(2′-hydroxypalmitoyl) octadecas-phinga-4, 8-dienine (soya cerebroside Ⅰ,Ⅱ). Conclusion Compound I is a new compound. Compound Ⅱ is obtained from this plant for the first time.

国家自然科学基金(30260014);云南省中青年学术和技术带头人后备人才培养基金资助(YP0024)