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[摘要]
莲心碱系睡莲科莲属植物莲Nelumbonucifera的莲子心中的主要生物碱,具有广泛的抗心率失常作用。过去曾用化学降解法推定其结构,迄今未见对莲心碱结构作详细的波谱解析。为求结构的准确性,作者用2D-NMR等现代波谱技术,对莲心碱的结构作了详细的解析,其结论与文献所记载的莲心碱的结构完全吻合。
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[Abstract]
The chemical structure of liensinine (1) isolated from Nelumbo nucifera Gaertn. was deter mined by means of chemical degradation by Pan et al in 1962, pnd was elucidated by simple 1HNMR in 1984. Recently,the authors further elucidated the sturcture of liensinine on the basis of spectroscopic analysis including HREI-MS, DEPT, 2D-NMR of 1H-13C COSY,1H-1H COSY and NOE sy.The results of spectral analysis indicated that the structure of liensinine is identical with that reported in literature.
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