[关键词]
[摘要]
近年来中药及其制剂的安全用药备受国内外学者的关注。综述了甘草酸苷注射液、复方甘草口服液、复方甘草片等甘草类制剂不良反应的研究进展,从其引发的内分泌、心血管、神经、生殖、消化、免疫等多个系统的不良反应进行总结阐述,其中主要涉及到的作用机制包括雌激素样作用、糖皮质激素样作用、盐皮质激素样作用等,希望能够指导甘草及其制剂在临床上的合理使用。
[Key word]
[Abstract]
In recent years, the safety of traditional Chinese medicine and its preparations have attracted much attention. The research progress of the adverse reactions of glycyrrhizin injection, compound licorice oral liquid, compound licorice tablets and other licorice preparations is reviewed. From the licorice-induced endocrine, cardiovascular, neurological, reproductive, digestive, immune and other systemic adverse reactions is summarized. The main mechanisms involved are estrogen-like effects, glucocorticoid-like effects, and mineralocorticoid-like effects, hope to guide the correct use of licorice and its preparations in clinical practice.
[中图分类号]
[基金项目]
国家自然科学基金资助项目(81573825)