目的 探讨丹芍消炎合剂联合静脉抗生素治疗湿热型亚急性盆腔炎的临床效果。方法 83 例确诊为亚急性盆腔炎患者随机分为2 组;对照组41 例,每12 h 静脉滴注头孢西丁2 g(头孢类过敏者改用克林霉素1 g),使用至临床症状、体征改善后的24 h,同时po 强力霉素100 mg,2 次/d,共2 周;治疗组42 例,在对照组基础上po 芍消炎合剂35 mL/次,3次/d,连续2 周,比较两组患者的临床疗效与不良反应。结果 治疗组的总有效率为97.6%、愈显率76.1%,静脉抗生素使用(3.52±0.94)d;对照组总有效率90.24%、愈显率29.2%,静脉抗生素使用(4.95±1.18)d,两组比较差异有统计学意义(P<0.01);且两组均未发生不良反应。结论 丹芍消炎合剂联合静脉抗生素治疗亚急性盆腔炎疗效确切,能明显改善患者的临床症状、缩短静脉抗生素的使用时间,值得临床推广应用。

Objective To investigate clinical effect of Danshao Anti-inflammatory Liquid combined with levofloxacin therapy in the treatment of subacute pelvic inflammatory disease. Methods Eighty-three patients with chronic pelvic inflammatory disease were randomly divided into control (n = 41) and treatment (n = 42) groups. The patients in the control group were iv administered with levofloxacin 2 g per 12 h and po administered with levofloxacin 100 mg, 2 time/d, for 14 d. While the patients in the treatment group were po administered with Danshao Anti-inflammatory Liquid, 35 mL/time, 3 time/d. Clinical effects of the two groups were compared. Results After treatment, the treatment group had total effective rate as 97.6%, which was obviously higher than that of the control group (90.24%). The difference between the two groups was statistical significant (P < 0.01). In addition, the using of the combination solution of Danshao Anti-inflammatory Liquid and vein antibiotics could decrease the using period of vein antibiotics. Conclusion Danshao Anti-inflammatory Liquid combined with levofloxacin therapy provides precise effect in treating subacute pelvic inflammatory disease, can remarkably improve clinical symptoms in patients, and it is worthy of promotion and application.

上海市科学技术委员会科研计划项目课题(12401901904)