目的 探讨舒乐安定的助眠效果以及药物依赖情况.方法 选取2012年4月—2014年3月在海口市第四人民医院治疗的失眠症患者124例,随机分为观察组(n＝62,给予舒乐安定)和对照组(n＝62,给予阿米替林),观察两组疗效以及药物依赖情况,同时采用纽芬兰纪念大学幸福度量表,对两组患者治疗前后进行问卷调查.结果 观察组总有效率为93.55%,明显高于对照组的79.03%,差异有统计学意义(P <0.05);观察组和对照组治疗后幸福度总分均较治疗前有所增高,差异有统计学意义(P <0.05);观察组治疗后幸福度总分为(37.18±5.28)分,明显高于对照组的(30.22±4.17)分,差异有统计学意义(P <0.05);观察组有33例产生药物依赖性,占53.23%,而对照组有18例产生药物依赖性,占29.03%,两组差异有统计学意义(P <0.05).结论 舒乐安定片治疗失眠症有较好的疗效,但仍存在药物依赖性的问题.

Objective To investigate the hypnosis effect and drug dependency of Estazolam Tablet. Methods From April 2012 to March 2014 in Fourth People's Hospital of Haikou, the insomnia patients (124 cases) were randomly divided into observation group (n= 62, estazolam) and control group (n = 62, amitriptyline), the curative effect and drug dependence in two groups were observed, and at the same time, the patients in two groups before and after treatment were investigated by questionnaire survey using Memorial University of Newfoundland Happiness measure table. Results The total effective rate of observation group was 93.55%, significantly higher than that in the control group (79.03%), and the difference was statistically significant (P <0.05); The happiness scores of observation group and control group after treatment were increased than those before treatment, and the difference was statistically significant (P <0.05); The happiness score of patients in the observation group was (37.18 ± 5.28), significantly higher than that of the control group (30.22 ± 4.17), and the difference was statistically significant (P <0.05); There were 33 cases in observation group producing drug dependence, accounted for 53.23%, while the control group had 18 cases producing drug dependence, accounted for 29.03%, with significant difference between two groups (P <0.05). Conclusion Estazolam Tablet in the treatment of insomnia has a good effect, but there is still the problem of drug dependence.