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目的 观察注射用红花黄色素治疗不稳定型心绞痛的临床效果。方法 80例患者随机分为红花黄色素治疗组和对照组。对照组常规给予硝酸脂类、钙通道阻滞剂、β受体阻滞剂及阿司匹林治疗。治疗组在此基础上加用注射用红花黄色素100 mg加入0.9%氯化钠注射液250 mL中静滴,每日1次,14 d为一疗程。观察治疗前、后临床症状,每日心绞痛发作次数,持续时间,疼痛程度,心率、血压变化情况、硝酸甘油片的消耗量。结果 两组治疗后血脂情况都有所改善,但红花黄色素治疗组效果要优于对照组(P<0.01)。红花黄色素治疗组和对照组患者临床有效率分别为97.00%和86.00%,差异有统计学意义(P<0.05)。结论 红花黄色素治疗冠心痛心绞痛疗效确切。
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[Abstract]
Objective To evaluate the efficacy of Safflor Yellow Injection for the treatment of angina pectoris with coronary heart disease (CHD). Methods Eighty patients were divided into control group, which was given nitric acid lipid, calcium channel blockers, beta blockers and aspirin therapy and safflor yellow group. There are 40 patients in each group. Besides conventional therapy, the patients in safflor yellow group received the iv injection of 100 mg safflor yellow in 250 mL 0.9% sodium chloride injection. Clinical signs were observed before and after the treatment, such as daily episodes of angina pectoris, continuous time, the degree of pain, changes in heart rate and blood pressure, and consumption of nitroglycerin tablets. Results After the treatment, blood lipid in both groups had been improved, but the effect in safflower yellow pigment group is superior to the control group (P<0.01). The total effective rates of safflor yellow group and control group were 97% and 86% respectively (P<0.05﹚. Conclusion The treatment with Safflor Yellow Injection for angina pectoris with coronary heart disease is safe and effective.
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