目的 探究榆栀止血颗粒联合富马酸亚铁治疗月经量过多所致贫血的临床疗效。方法 选取曲靖市第一人民医院2018年4月-2019年1月收治的164例月经量过多所致贫血患者作为研究对象，根据治疗方案将患者分为对照组和观察组，每组82例。对照组患者口服富马酸亚铁咀嚼片，0.2 g/次，3次/d；观察组患者在对照组治疗的基础上口服榆栀止血颗粒，月经第1天开始服用，1袋/次，3次/d，经期服用，血止即停。观察两组患者的临床疗效，比较两组治疗前后的血红蛋白（Hb）、红细胞（RBC）、血浆白蛋白（PA）和红细胞压积（HCT）的水平。结果 治疗后，观察组总有效率为92.7%，显著高于对照组的82.9%，两组比较差异具有统计学意义（P<0.05）。治疗后，两组患者Hb、RBC、PA和HCT水平均显著升高（P<0.05）；治疗后，观察组患者治疗后Hb、RBC、PA和HCT显著高于对照组，差异具有统计学意义（P<0.05）。结论 榆栀止血颗粒联合富马酸亚铁治疗月经量过多所致贫血具有显著疗效，值得临床推广。

Objective To investigate the clinical effect of Yuzhi Zhixue Granules combined with ferrous fumarate on anemia caused by excessive menstruation. Methods A total of 164 patients with anemia caused by excessive menstruation admitted to The First People's Hospital of Qujing from April 2018 to January 2019 were selected as the research subjects. According to the treatment plan, the patients were divided into control group and observation group, with 82 cases in each group. Patients in the control group were po administered with Ferrous Fumarate Chewable Tablets, 0.2 g/time, three times daily. Patients in the observation group were po administered with Yuzhi Zhixue Granules on the basis of control group, the first day of menstruation began to take, 1 bag/time, three times daily, menstrual administration, blood stop immediately. After treatment, the clinical efficacy in two groups was observed, and the levels of Hb, RBC, PA, and HCT before and after treatment between two groups were compared. Results After treatment, the total effective rate of the observation group was 92.7%, which was significantly higher than 82.9% in the control group, and the difference between two groups was statistically significant (P<0.05). After treatment, the levels of Hb, RBC, PA and HCT in two groups were significantly increased (P<0.05). After treatment, Hb, RBC, PA and HCT in the observation group were significantly higher than those in the control group, with statistical significance (P<0.05). Conclusion Yuzhi Zhixue Granules combined with ferrous fumarate in treatment of anemia caused by excessive menstruation has significant curative effect, worth clinical promotion.

R984

国家重点研发计划项目（2019YFC1711200）