目的 探讨宫炎平胶囊联合阿奇霉素片治疗淋菌性阴道炎的临床疗效。方法 选取2016年1月-2018年1月延安大学附属医院收治的112例淋菌性阴道炎患者为研究对象，将患者随机分为对照组和治疗组，每组各56例。对照组口服阿奇霉素片，首日0.5 g，之后每日0.25 g。治疗组在对照组的基础上口服宫炎平胶囊，3粒/次，3次/d。两组均治疗2周。观察两组患者的临床疗效，同时比较两组的临床症状消失时间和血清炎症因子水平。结果 治疗后，对照组和治疗组总有效率分别为67.80%、89.30%，两组比较差异具有统计学意义（P<0.05）。治疗后，治疗组瘙痒、白带异常、分泌物异常消失时间均显著短于对照组，两组比较差异具有统计学意义（P<0.05）。治疗后，两组白细胞介素-2（IL-2）、白细胞介素-8（IL-8）和白细胞介素-13（IL-13）水平均显著降低，同组治疗前后比较差异具有统计学意义（P<0.05）；治疗后，治疗组血清炎性因子水平显著低于对照组，两组比较差异具有统计学意义（P<0.05）。结论 宫炎平胶囊联合阿奇霉素片治疗淋菌性阴道炎具有较好的临床疗效，可迅速达到抗炎抑菌的作用，且安全性较好，复发率较低，具有一定的临床推广应用价值。

Objective To investigate the clinical effect of Gongyanping Capsules combined with Azithromycin Tablets in treatment of gonococcal vaginitis. Methods Patients (112 cases) with gonococcal vaginitis in Yan'an University Affiliated Hospital from January 2016 to January 2018 were randomly divided into control and treatment groups, and each group had 56 cases. Patients in the control group were po administered with Azithromycin Tablets 0.5 g on the first day, and 0.25 g daily after that. Patients in the treatment group were po administered with Gongyanping Capsules, 3 grains/time, three times daily. Patients in two groups were treated for 2 weeks. After treatment, the clinical efficacy was evaluated, and the disappearance time of clinical symptoms and serum inflammatory factor levels in two groups were compared. Results After treatment, the clinical efficacy in the control and treatment groups was 67.80% and 89.30%, respectively, and there were differences between two groups (P < 0.05). After treatment, the disappearance times of itching, leucorrhea abnormality, and secretion abnormality in the treatment group were significantly shorter than those in the control group, and there were differences between two groups (P < 0.05). After treatment, the serum levels of IL-2, IL-8, and IL-13 in two groups were significantly decreased, and the difference was statistically significant in the same group (P < 0.05). After treatment, the serum inflammatory factor levels in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P < 0.05). Conclusion Gongyanping Capsules combined with Azithromycin Tablets has good clinical efficacy in treatment of gonococcal vaginitis, can quickly achieve the effect of anti-inflammatory and bacteriostasis, with good safety and low recurrence rate, which has a certain clinical application value.