目的 了解2017年武汉大学人民医院注射用复合辅酶的用药情况，促进辅助用药的合理使用。方法 按科室5%抽查出院病历数，回顾性分析2017年武汉大学人民医院注射用复合辅酶的基本情况，并分析其用药合理性。结果 使用注射用复合辅酶的男性患者多于女性患者，年龄主要分布在60岁以上，使用人数最多的科室为心血管内科，人数达74例；人均使用剂量最高的科室为老年病科，为6 130 U；平均使用天数最长科室也是老年病科，长达21.43 d。抽查的456份病历中有100份用药不合理，不合理使用率为21.93%，主要存在的问题为无适应症用药（10.31%）和溶媒选择不当（10.31%）。结论 2017年武汉大学人民医院注射用复合辅酶的临床使用存在着某些不合理的情况，应加强其规范使用的管理。

Objective To observe the utilization of Coenzyme Complex for injection in Renmin Hospital of Wuhan University in 2017. Methods Sampling 5% cases of the medical records from clinical departments in 2017, to find out the basic situation of the use of Coenzyme Complex for injection in Renmin Hospital of Wuhan University in 2017, and analyze the rationality of drug use. Results The male was more than female using Coenzyme Complex for injection. The age of most patients was above 60 years old. The department with the largest number of users (74 cases) was Department of Cardiovascular Medicine. The department with the highest dose per capita (6 130 U) was Department of Geriatrics. Department of Geriatrics was also the department with the longest average use days (21.43 d). 456 cases were selected, and 100 cases were unreasonable. Thus the unreasonable utilization rate was 21.93%, and no indication of drug use (10.31%) and improper selection solvent (10.31%) were the main problems. Conclusion There is an irrational use of Coenzyme Complex for injection in Renmin Hospital of Wuhan University in 2017, thus the use and management should be strengthened and regulated.