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[摘要]
目的 分析天津市津南区咸水沽医院平喘药的应用情况和趋势,为临床合理用药提供参考。方法 对2015—2017年平喘药的应用品种、销售金额、用药频度(DDDs)及日均费用(DDC)进行统计和分析。结果 本院平喘类药物有β肾上腺素受体激动剂、M胆碱受体拮抗剂、黄嘌呤类药物、肾上腺皮质激素、抗白三烯类药物和中成药6大类。2015—2017年平喘药的销售金额呈先上升后下降的趋势。销售金额及构成比的排序均为β肾上腺素受体激动剂、肾上腺皮质激素、黄嘌呤类药物、中成药、抗白三烯类药物和M胆碱受体拮抗剂。销售金额排名前15位的平喘类药物主要是β肾上腺素受体激动剂,其次是中成药类药物。DDDs排名前15位的抗高血压药物主要是β肾上腺素受体激动剂和肾上腺皮质激素这两类药物,吸入用异丙托溴铵溶液的DDDs居首位。沙美特罗替卡松粉吸入剂的DDC居首位。结论 天津市津南区咸水沽医院平喘类药物品种齐全,使用基本合理,但个别药品的选择和使用上存在不合理用药现象,提示临床医师在指导哮喘患者应用平喘类药物时应严格明确用药指征。
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[Abstract]
Objective To analyze the application and trends of antiasthmatic drugs in Jinnan Xianshuigu Hospital of Tianjin City, and to provide reference for clinical rational drug use. Methods The statistics on the application categories, sales amount, frequency of drug use (DDDs), and daily average cost (DDC) of antiasthmatic drugs were calculated and analyzed from 2015 to 2017. Results The antiasthmatic drugs in Jinnan Xianshuigu Hospital of Tianjin City include β-adrenoceptor agonists, M-choline receptor antagonists, xanthines, adrenocortical hormones, anti-leukotrienes, and Chinese patent medicines. From 2015 to 2017, the sales amount of antiasthmatic drugs rose first, and then decreased. The antiasthmatic drugs in order of sales amount and composition ratio were ranked as β adrenergic receptor agonists, adrenal cortical hormones, xanthine drugs, Chinese patent medicines, anti-leukotriene drugs, and M-choline receptor antagonists. The top 15 antiasthmatic drugs ranked in the sales amount were β adrenergic receptor agonists, followed by Chinese patent medicines. The top 15 antihypertensive drugs ranked by DDDs were mainly β adrenergic receptor agonists and adrenocortical hormone drugs. DDDs of Ipratropium Bromide Solution for inhalation was in the first place. DDC of Salmeterol Xinafoate and Fluticasone Propionate Powder for inhalation ranked the first. Conclusion The antiasthmatic drugs in Jinnan Xianshuigu Hospital of Tianjin City are complete and their use is basically reasonable. However, there are unreasonable drug use phenomena in the selection and use of individual drugs, suggesting that clinicians should define the indications of antiasthmatic drugs strictly when guiding asthma patients to apply antiasthmatic drugs.
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