[关键词]
[摘要]
目的 探讨新血宝胶囊联合多维铁口服溶液治疗妊娠期缺铁性贫血的临床疗效。方法 选取2021年6月—2023年6月在广州市妇女儿童医疗中心柳州医院治疗的妊娠期缺铁性贫血患者124例,随机分为对照组(62例)和治疗组(62例)。对照组患者口服多维铁口服溶液,15 mL/次,2次/d。治疗组患者在对照组基础上口服新血宝胶囊,2 粒/次,3次/d。两组患者连续治疗4周。观察两组患者临床疗效,比较治疗前后两组患者血红蛋白(Hb)、平均血红蛋白含量(MCH)、平均血红蛋白浓度(MCHC)、铁蛋白和总铁结合力(TIBC)水平。结果 治疗后,治疗组总有效率为96.77%,明显高于对照组的87.10%(P<0.05)。治疗后,两组Hb、MCH、MCHC和铁蛋白水平较治疗明显升高,而TIBC水平明显降低(P<0.05),且治疗组这些指标水平明显好于对照组(P<0.05)。结论 新血宝胶囊联合多维铁口服溶液治疗妊娠期缺铁性贫血具有较好的临床疗效,可显著改善患者的贫血指标和铁代谢指标,且不良反应少。
[Key word]
[Abstract]
Objective To explore the efficacy of Xinxuebao Capsules and Multivitamin Iron Oral Solution in treatment of iron deficiency anemia during pregnancy. Methods Patients (124 cases) with iron deficiency anemia during pregnancy in Guangzhou Women and Children's Medical Center Liuzhou Hospital from June 2021 to June 2023 were randomly divided into control (62 cases) and treatment (62 cases) group. Patients in the control group were po administered with Multivitamin Iron Oral Solution, 15 mL/time, twice daily. Patients in the treatment group were po administered with Xinxuebao Capsules on the basis of the control group, 2 grains/time, three times daily. Patients in two groups were treated for 4 weeks. After treatment, the clinical evaluations was evaluated, the levels of Hb, MCH, MCHC, ferritin and TIBC in two groups before and after treatment were compared. Results After treatment, the clinical effective rate of the treatment group was 96.77%, which was significantly higher than that of the control group (87.10%, P<0.05). After treatment, the levels of Hb, MCH, MCHC and ferritin in two groups were significantly higher than those in the treatment group, while the level of TIBC was significantly decreased in two groups (P<0.05), and the level of these indexes in the treatment group was significantly better than that in the control group (P<0.05). Conclusion Xinxuebao Capsules combined with Multivitamin Iron Oral Solution has a good clinical effect in the treatment of iron deficiency anemia during pregnancy, which can significantly improve the anemia index and iron metabolism index with less adverse reactions.
[中图分类号]
R973
[基金项目]
广西壮族自治区卫生健康委自筹经费科研课题(Z-B20232038)