[关键词]
[摘要]
尿囊素是一种天然的、安全的,无毒的咪唑类杂环化合物,具有多种药理作用。随着尿囊素药理特性的不断深入研究,发现其涉及到多种分子机制,如激活咪唑啉受体、提高能量代谢、抗氧化应激、抗炎等。归纳总结了尿囊素的药理作用机制,以期为尿囊素的后续研究和开发利用提供参考。
[Key word]
[Abstract]
Allantoin is a natural, safe, non-toxic imidazole heterocyclic compound, which has a variety of pharmacological effects. With the further study of the pharmacological properties of allantoin, it involves a variety of molecular mechanisms, such as activation of imidazoline receptors, improvement of energy metabolism, antioxidant stress, anti-inflammatory, etc. Therefore, this paper summarized the mechanism of allantoin, so as to provide a reference for the follow-up research and development of allantoin.
[中图分类号]
R285
[基金项目]
国家自然科学基金青年科学基金资助项目(82000842);广东省基础与应用基础研究基金资助项目(2021A1515010151)