目的 探讨“4＋7”带量采购政策对上海市浦东新区人民医院口服降糖药使用的影响及带来的经济效应，为政策制定和完善提供理论依据。方法 对上海市浦东新区人民医院“4＋7”带量采购政策实施前后1年口服降糖药的单价、使用量、销售金额、用药频度（DDDs）、日均费用（DDC）等进行分析，并计算“4＋7”带量采购政策后的实际节省费用。结果 “4＋7”带量采购政策实施后，中选品种阿卡波糖单价显著降低，降价幅度达41.28%，其他未中标品种的价格均未变；中选品种阿卡波糖和格列美脲的DDDs有明显变化，DDC下降显著；阿卡波糖节省费用近6万元。结论 “4＋7”带量采购政策实施使上海市浦东新区人民医院口服降糖药中选品种的日均费用大幅下降，切实减轻了患者和医保的负担，可为优化药品价格调整机制提供参考。

Objective To explore the impact of “4+7” volume procurement policy on the utilization of oral antidiabetic drugs and the economic effectiveness in Shanghai Pudong New Area People’s Hospital, and to provide a reference for the improvement of policy. Methods To analyze the unit price, consumption amount, consumption sum, DDDs and DDC of oral hypoglycemic drugs in Shanghai Pudong New Area People's Hospital one year before and after the implementation of “4+7” procurement policy, and calculate the actual cost savings after “4+7” procurement policy. Results After the implementation of “4+7” purchasing policy with quantity, the unit price of acarbose of the selected variety was significantly reduced, with a reduction of 41.28%, while the prices of other unsuccessful varieties remained unchanged. DDDs and DDC of acarbose and glimepirea were significantly decreased. Acarbose saves nearly 60 000 yuan. Conclusion The implementation of the “4+7” purchase policy with quantity significantly reduced the average daily cost of selected oral hypoglycemic drugs in Shanghai Pudong New Area People's Hospital, effectively alleviating the burden of patients and medical insurance, which can provide reference for optimizing the drug price integration mechanism.

R977