海洋中复杂的生存条件造就了海洋天然产物区别于陆地天然产物的独特结构和多样的生理活性。从海洋生物中提取的活性物质大多具有良好的抗炎、抗肿瘤、免疫调节和治疗心血管疾病等作用。心血管疾病又称循环系统疾病，在我国的患病率和死亡率不断增加，成为城乡居民致死和致残的首要原因。就近年来海洋天然产物在治疗心血管疾病方面抗血栓形成、改善心功能、抗高血压的作用机制研究进展进行综述。

The complex living conditions in the ocean result in the unique structure and various active substances of marine natural products, which are different from those on land. Most of the active substances extracted from marine organisms have good effects on anti-inflammatory, anti-tumor, immune regulation and treatment of cardiovascular diseases. Cardiovascular disease, as known as circulatory system disease, is currently increasing in morbidity and mortality in China, and it is becoming the leading cause of death and disability among people. This study provides a reference on marine natural products in the prevention and treatment of cardiovascular diseases, such as anti-thrombosis, improving heart function, and anti-hypertensive effect in the recent years.

R972

福建省中青年教师教育科研项目（JAT190620；JAT200227）