植物内生菌是一种不可多得的微生物资源，具有广泛的应用价值，特别是药用植物内生菌近年来受到越来越多学者的青睐。内生菌的代谢产物是新型化合物和药理学的潜在来源，能够帮助人类解决抗生素的耐药性、植物遭遇病虫害侵袭以及动物的健康等问题，因此对具有抗菌作用的内生菌进行总结具有重要意义。从抑菌机制、抑菌活性次生代谢产物方面进行综述，并对植物内生菌的开发利用进行展望。

Endophytic bacteria are a rare microorganism resource and have a wide range of application value. In recent years, more and more scholars devote themselves to the study of endophytic bacteria in medicinal plants. Metabolites of endophytic bacteria are potential sources of novel compounds and pharmacology, which can help humans solve problems, such as antibiotic resistance, plant disease and insect attacks, and animal health, etc. Therefore, it is great significant to systematically summarize endophytic bacteria with antimicrobial effects. In this paper, antimicrobial mechanisms and secondary metabolites of plant endophytic bacteria are reviewed, and the development and utilization of plant endophytic bacteria are prospected.

R286.8

海南省自然科学基金资助项目（820RC624）