目的 调查分析氟比洛芬酯注射液的临床应用情况并进行合理用药评价。方法 从医院管理系统中抽取2019年1月1日—2020年12月31日天津市宝坻区人民医院应用氟比洛芬酯注射液的住院患者临床资料和用药的基本情况资料。选择氟比洛芬酯注射液用量排名前5位的科室，每个科室随机抽取40例患者，对抽取调查的200例患者氟比洛芬酯注射液的适应症、用法用量等进行用药合理性评价。结果 2019年1月1日—2020年12月31日住院患者应用氟比洛芬酯注射液共2 970例，其中男性1 683例，女性1 287例；骨科等开展手术的外科科室使用量较多（33.87%）；抽取的200例患者中，5例（2.5%）为超适应症用药，3例（1.5%）为联合用药不适宜，2例（1.0%）为用药选择不适宜，9例（4.5%）为用药疗程不适宜，4例（2.0%）患者年龄大于60岁患者使用日剂量为200 mg。结论 医院应当进一步采取科学管理策略，加强氟比洛芬酯注射液临床使用管理。

Objective To investigate and analyze the clinical application of Flurbiprofen Axetil Injection and evaluate its rational use. Methods The clinical data and medication information of inpatients receiving Flurbiprofen Axetil Injection in Baodi Hospital from January 1, 2019 to December 31, 2020 were extracted from the hospital management system. The top 5 departments of Flurbiprofen Axetil Injection dosage were selected, 40 patients were randomly selected from each department, and the indications, usage and dosage of flurbiprofen ester injection in 200 patients were evaluated for rationality of drug use. Results From January 1, 2019 to December 31, 2020, a total of 2 970 hospitalized patients received Flurbiprofen Axetil Injection, including 1 683 males and 1 287 females. Orthopedics and other surgical departments used more (33.87%). Among the 200 patients selected, 5 (2.5%) were off-label, 3 (1.5%) were unsuitable combination, 2 (1.0%) were unsuitable choice of medication, 9 (4.5%) were unsuitable course of medication, and 4 (2.0%) were older than 60 years and received a daily dose of 200 mg. Conclusion Hospitals should further adopt scientific management strategies to strengthen clinical management of Flurbiprofen Ester Injection.

R969.3