目的 探讨丹红注射液治疗冠心病心绞痛的疗效观察。方法 选取2016年6月—2018年5月郑州市金水区总医院收治的80例冠心病心绞痛患者，随机分为对照组和治疗组，每组各40例。对照组口服阿司匹林肠溶片100 mg，硫酸氢氯吡格雷片75 mg，阿托伐他汀钙片40 mg，均为1次/d。治疗组在对照组的基础上静脉滴注丹红注射液，100 mL加入生理盐水40 mL，1次/d。两组治疗4周。观察两组患者心电图疗效，比较治疗前后两组患者临床症状积分、血液流变学指标、心功能分级和不良反应。结果 治疗后，治疗组总有效率为95.0%，明显高于对照组的75.0%（P<0.05）。治疗后，两组临床症状积分均显著降低（P<0.05），且治疗组临床症状积分明显低于对照组（P<0.05）。治疗后，两组患者血液流变学指标和心功能分级均较治疗前显著改善（P<0.05）；且治疗组改善效果优于对照组（P<0.05）。治疗组患者不良反应发生率明显低于对照组（P<0.05）。结论 常规疗法联合丹红注射液治疗冠心病心绞痛可达到更好的疗效。

Objective To investigate the curative effect of Danhong Injection in treatment of angina pectoris of coronary heart disease. Methods Patients (80 cases) with angina pectoris of coronary heart disease in Zhengzhou Jinshui General Hospital from June 2016 to May 2018 were randomly divided into control and treatment groups, and each group had 40 cases. Patients in the control group were po administered with Aspirin Enteric-coated Tablets 100 mg, Clopidogrel Hydrogen Sulphate Tablets 75 mg, and Atorvastatin Calcium Tablets 40 mg, once daily. Patients in the treatment group were iv administered with Danhong Injection on the basis of the control group, 100 mL added into normal saline 40 mL, once daily. Patients in two groups were treated for 4 weeks. After treatment, the ECG evaluation was evaluated, the clinical symptom scores, hemorheological indexes, cardiac function grading, and adverse reactions in two groups before and after treatment were compared. Results After treatment, the clinical effective rate of the treatment group was 95.0%, which was significantly higher than 75.0% of the control group (P < 0.05). After treatment, clinical symptom scores in both groups were significantly decreased (P < 0.05), and the clinical symptom score of the treatment group was significantly lower than that of the control group (P < 0.05). After treatment, hemorheology indexes and cardiac function grading in two groups were significantly improved compared with before treatment (P < 0.05). After treatment, the improvement of hemorheology and cardiac function in the treatment group was better than that in the control group (P < 0.05). The incidence of adverse reactions in the treatment group was significantly lower than that in the control group (P < 0.05). Conclusion The routine therapy combined with Danhong Injection can achieve better effect in the treatment of angina pectoris of coronary heart disease.

R972