我国恶性肿瘤发病人数居全球第一，而感染是恶性肿瘤常见的并发症，严重影响恶性肿瘤患者的疗效，延长住院时间，增加治疗费用，成为恶性肿瘤患者死亡的重要原因。近年来，随着抗菌药物的广泛应用，恶性肿瘤患者发生多重耐药菌感染比率逐年升高，对患者造成极大危害。因此提升对恶性肿瘤患者发生多重耐药菌感染的危险因素的认识至关重要，故对恶性肿瘤患者发生多重耐药菌感染的危险因素进行综述，以期为临床提供预防多重耐药菌感染的参考。

The number of cancer patients in China ranks first in the world, and infection is a common complication of cancer, which seriously affects the treatment effect of cancer patients. Prolonging hospital stay and increasing treatment costs have become an important cause of death of cancer patients. In recent years, with the wide application of antibiotics, the infection rate of multidrug resistant organisms (MDRO) in patients with malignant tumor is increasing year by year, which causes great harm to patients. Therefore, it is very important to improve the understanding of the risk factors of MDRO infection in patients with malignant tumor, so this paper reviews the risk factors of MDRO infection in patients with malignant tumor, in order to provide reference for clinical prevention of MDRO infection.

R979.1

国家自然科学基金资助项目（81703454）