目的 分析江苏省南京地区2017—2019年53家医院抗流感药物的临床应用情况与变化趋势，为其临床合理使用提供参考依据。方法 采用用药频度（DDDs）排序法与金额排序法，对南京地区53家医院2017—2019年使用的抗流感药物的品种、销售金额、构成比、用药频度（DDDs）、限定日费用（DDC）等进行回顾性统计和分析。结果 2017—2019年，南京地区抗流感药物的年销售金额与年DDDs逐年增长；炎琥宁与奥司他韦2种药物的销售金额连续3年位列前茅，且所占总销售金额的比例3年均超过50%。金刚烷胺、炎琥宁、板蓝根与奥司他韦4种药物的DDDs值连续3年位于前4位，且所占总DDDs的比例3年均超过80%，金刚乙胺持续排在末尾。结论 抗流感药物在南京地区医院应用广泛，销售金额与使用量均呈快速增长的趋势，部分药物的DDC呈降低趋势。

Objective To analyze the application of anti-influenza virus drugs in 53 hospitals in Nanjing area from 2017 to 2019 and provide a reference for its clinical.Methods Using the medication frequency (DDDs) and the sum of money of consumption (DDC), to analysis the varieties, sales amount, composition ratio, medication frequency and daily drug cost of anti-influenza virus drugs in 53 hospitals in Nanjing area in the study of retrospective statistics.Results The total amount and DDDs of use of anti-influenza virus drugs had increased year by year. The three-year sales of Oseltamivir and Yanhuning were ranked in the top three, and the proportion were more than 50%. The three-year DDDs of Oseltamivir, Amantadine, Yanhuning and Banlangen were ranked in the top four, and the proportion were more than 80%. Rimantadine continue to be at the end.Conclusion The anti-influenza virus drugs are widely used in hospitals in Nanjing, the sales amount and usage as a whole showed a trend of stabilization after growth. The DDC of the some drugs is decresing.

R978.7

江苏省政策引导类计划项目（BR2020043）；南京大学医院管理研究所管理项目课题（NDYG2019006）