目的 观察舒肝颗粒联合光子嫩肤治疗痤疮炎性红斑的临床疗效。方法 收集2019年10月—2020年10月天津市中医药研究院附属医院皮肤科门诊收治的90例痤疮炎性红斑患者，随机分为舒肝颗粒组、光子嫩肤组和联合治疗组，每组各30例。舒肝颗粒组患者口服舒肝颗粒，3 g/次，2次/d。光子嫩肤组患者采用光子治疗仪进行治疗。联合治疗组口服舒肝颗粒，同时接受光子嫩肤治疗。治疗12周。观察3组的临床疗效，比较3组红斑绝对分值的变化。结果 治疗后，舒肝颗粒组总有效率是90.0%，光子嫩肤组总有效率是93.3%，联合治疗组总有效率是100.0%，舒肝颗粒组、光子嫩肤组的总有效率均低于联合治疗组（P<0.05）。治疗后，3组红斑绝对分值均较治疗前显著升高（P<0.05）；治疗后，联合治疗组红斑绝对分值高于同期舒肝颗粒组、光子嫩肤组（P<0.05）。结论 舒肝颗粒联合光子嫩肤治疗痤疮后红斑具有较好的临床疗效，具有一定的推广应用价值。

Objective To observe the clinical efficacy of Shugan Granules combined with photorejuvenation in the treatment of acne inflammatory erythema. Methods A total of 90 patients with acne inflammatory erythema admitted to the Department of Dermatology of Affiliated Hospital of Tianjin Academy of Traditional Chinese Medicine from October 2019 to October 2020 were randomly divided into Shugan Granules group, photorejuvenation group and combined treatment group, with 30 patients in every group. Patients in Shugan Granules group were po administered with Shugan Granules, 3 g/time, twice daily for 12 weeks. Patients in photorejuvenation group were treated with photon therapy instrument. Patients in combined treatment group took Shugan Granules and received photonic skin treatment at the same time. The clinical efficacy of the three groups was observed, and the absolute score of erythema in the three groups was compared. Results After treatment, the total effective rate of Shugan Granules group was 90.0%, the total effective rate of photorejuvenation group was 93.3%, and the total effective rate of the combined treatment group was 100.0%. The total effective rate of Shugan Granules group and photorejuvenation group were both lower than the combined treatment group (P<0.05). After treatment, the absolute scores of erythema in 3 groups were significantly higher than those before treatment (P<0.05); After treatment, the absolute score of erythema in combined treatment group was higher than that in Shugan Granules group and photorejuvenation group (P<0.05). Conclusion Shugan Granules combined with photorejuvenation has a good clinical effect in the treatment of acne inflammatory erythema, which has a certain value of popularization and application.

R986