目的 分析天津市津南医院第二类精神药品的使用情况和变化趋势，为促进临床合理应用第二类精神药品提供依据。方法 对2017—2019年天津市津南医院第二类精神药品的销售量、销售金额、用药频度（DDDs）、日均药费（DDC）、药品排序比（B/A）进行统计和分析。结果 2017—2019年第二类精神药品的销售总金额呈现先下降后上升趋势。地佐辛注射液的销售金额始终居首位，2018—2019年佐匹克隆片、艾司唑仑片和咪达唑仑注射液的销售金额保持在前3位。2018—2019年，佐匹克隆片、艾司唑仑片和右佐匹克隆片的DDDs始终排名前3位。地佐辛注射液的DDC值较大，居首位。第二类精神药品的B/A基本均接近于1.00，同步性较好。结论 天津市津南医院第二类精神药品的使用基本合理，但个别药品存在不合理现象。

Objective To analyze the use situation and changing trend of the second class psychotropic drugs in Tianjin Jinnan Hospital, and to provide basis for promoting the rational application of the second class psychotropic drugs. Methods The sales volume, sales amount, frequency of drug use (DDDs), daily average drug cost (DDC), and drug ranking ratio (B/A) of the second class psychotropic drugs in Tianjin Jinnan Hospital from 2017 to 2019 were statistically analyzed. Results From 2017 to 2019, the total sales of the second class of psychotropic drugs showed a downward trend and then an upward trend. The sales amount of Dezocine Injection always ranked the first, and the sales amount of Zopiclone Tablets, Estazolam Tablets, and Midazolam Injections remained in the top three from 2018 to 2019. From 2018 to 2019, DDDs of Zopiclone Tablets, Estazolam Tablets, and Dexazopiclone Tablets had consistently ranked in the top three. The DDC value of Dezocine Injection was large, ranking the first. B/A of the second class psychotropic drugs were close to 1.00, and the synchronicity was good. Conclusion The use of the second class of psychotropic drugs in Tianjin Jinnan Hospital is basically reasonable, but some drugs are unreasonable.

R971

国家自然科学基金青年基金资助项目（81803524）