新型冠状病毒肺炎（COVID-19）于2019年12月在武汉爆发，目前尚无特效治疗药物，临床治疗以对症治疗、控制并发症为主。国家卫健委和多个省的诊疗方案中推荐藿香正气用于COVID-19医学观察期乏力伴胃肠不适或临床治疗期"湿邪、寒湿、疫毒"相关中医证型的治疗。藿香正气为常用的祛湿剂，有解表化湿、理气和中的功效，主要从药理研究和临床研究方面综述了藿香正气的抗病毒、抗炎和改善相关症状等的研究进展，并尝试探讨了藿香正气用于防治COVID-19的可能机制，以期为藿香正气防治COVID-19的应用提供参考。

The coronavirus disease 2019 (COVID-19) firstly outbroke in Wuhan on December 2019. Currently, there is no specific treatment drug for COVID-19, and the main clinical treatments are symptom relieving and complication controlling. The treatment protocols of National Health Commission and several provinces recommend Huoxiang Zhengqi for the treatment of patients with fatigue and stomach uncomfortable in observation period or patients with "dampness pathogen, cold-dampness or epidemic toxin" relevant symptoms in clinical treatment period. Huoxiang Zhengqi is frequently-used damp-clearing prescription and have efficacy of reliving superficies, dispersing dampness, and harmonizing stomach. The perspective of pharmacology and clinical trials of Huoxiang Zhengqi in antivirus, anti-inflammation and relieving symptoms are reviewed in this paper, and the possible mechanism of Huoxiang Zhengqi in prevention and treatment of COVID-19 is discussed, hoping to provide reference for applying Huoxiang Zhengqi in prevention and treatment of COVID-19.

R286.4

国家“重大新药创制”科技重大专项（2017ZX09301005）