目的 分析坤复康片联合司帕沙星治疗慢性盆腔炎的临床效果。方法 选择2017年2月-2019年3月在南阳市卧龙区第一人民医院治疗的慢性盆腔炎患者179例，随机分为对照组（89例）和治疗组（90例）。对照组患者口服司帕沙星片，0.1 g/次，1次/d。治疗组在对照组基础上口服坤复康片，3~4片/次，3次/d。两组患者连续治疗1个月。观察两组患者临床疗效，同时比较治疗前后两组患者白细胞介素-2（IL-2）、肿瘤坏死因子-α（TNF-α）和C反应蛋白（CRP）水平，及临床症状改善时间。结果 治疗后，对照组临床有效率为77.53%，显著低于治疗组的94.44%，两组比较差异有统计学意义（P<0.05）。治疗后，两组患者IL-2明显升高（P<0.05），而TNF-α和CRP水平显著降低（P<0.05），且治疗组患者IL-2、TNF-α和CRP水平改善效果明显优于对照组（P<0.05）。治疗后，治疗组患者宫颈举痛改善时间和小腹坠痛改善时间明显比对照组短，两组比较差异具有统计学意义（P<0.05）。结论 坤复康片联合司帕沙星治疗慢性盆腔炎，可快速缓解患者宫颈举痛改善时间和小腹坠痛等临床症状，临床疗效较好，安全可靠。

Objective To analyze the clinical effect of Kunfukang Tablets combined with sparfloxacin in treatment of chronic pelvic inflammation. Methods Patients (179 cases) with chronic pelvic inflammation in the First People's Hospital of Nanyang Wolong District from February 2017 to March 2019 were randomly divided into control (43 cases) and treatment (43 cases) groups. Patients in the control group were po administered with Sparfloxacin Tablets, 0.1 mg/time, once daily. Patients in the treatment group were po administered with Kunfukang Tablets on the basis of the control group, 3-4 tablets/time, three times daily. Patients in two groups were treated for 1 month. After treatment, the clinical efficacy was evaluated, and the IL-2, TNF-α, and CRP levels, and the improvement time of clinical symptoms in two groups before and after treatment were compared. Results After treatment, the clinical efficacy in the control group was 77.53%, which was significantly lower than 94.44% in the treatment group, and there were differences between two groups (P < 0.05). After treatment, the IL-2 levels in two groups were significantly increased (P < 0.05), but the TNF-α and CRP levels were significantly decreased (P < 0.05), and the IL-2, TNF-α and CRP levels in the treatment group were significantly better than those in the control group (P < 0.05). After treatment, the improvement time of cervical lifting pain and abdominal dropping pain in the treatment group was significantly shorter than that in the control group, and the difference was statistically significant between two groups (P < 0.05). Conclusion Kunfukang Tablets combined with sparfloxacin in treatment of chronic pelvic inflammation can rapidly relieve clinical symptoms such as cervical lifting pain and lower abdomen falling pain, which has better clinical efficacy with high safety and reliability.

R984