目的 探讨少腹逐瘀颗粒联合注射用醋酸曲普瑞林治疗子宫内膜异位症的临床疗效。方法 选取2017年11月—2018年10月在延安大学附属医院诊治的92例子宫内膜异位症患者为研究对象，所有患者按随机数字表法随机分为对照组和治疗组，每组各46例。对照组患者在月经来潮第1天肌肉注射注射用醋酸曲普瑞林，3.75 mg/次，1次/4周。治疗组患者在对照组治疗的基础上口服少腹逐瘀颗粒，1.6 g/次，3次/d。两组患者连续治疗3个月经周期。观察两组的临床疗效，比较两组的血清指标、视觉模拟评分法（VAS）评分和囊肿直径。结果 治疗后，对照组和治疗组的总有效率分别为78.26%、93.48%，两组比较差异有统计学意义（P<0.05）。治疗后，两组血清糖类抗原199（CA199）、恶性肿瘤特异性生长因子（TSGF）、促红细胞生成素（EPO）、血管内皮生长因子（VEGF）水平均显著降低，同组治疗前后比较差异具有统计学意义（P<0.05）；且治疗后治疗组CA199、TSGF、EPO、VEGF水平明显低于对照组，两组比较差异具有统计学意义（P<0.05）。治疗后，两组患者的VAS评分、囊肿直径均明显下降，同组治疗前后比较差异具有统计学意义（P<0.05）；且治疗后治疗组VAS评分、囊肿直径明显低于对照组，两组比较差异具有统计学意义（P<0.05）。结论 少腹逐瘀颗粒联合注射用醋酸曲普瑞林治疗子宫内膜异位症具有较好的临床疗效，可改善临床症状和体征，减轻疼痛，调节血清指标，具有一定的临床推广应用价值。

Objective investigate the clinical effect of Shaofu Zhuyu Granules combined with Triptorelin Acetate for injection in treatment of endometriosis. Methods Patients (92 cases) with endometriosis in Yan'an University Affiliated Hospital from November 2017 to October 2018 were randomly divided into control and treatment groups, and each group had 46 cases. Patients in the control group were intramuscular injection administered with Triptorelin Acetate for injection on the first day of menstruation, 3.75 mg/time, once every 4 weeks. Patients in the treatment group were po administered with Shaofu Zhuyu Granules on the basis of the control group, 1.6 g/time, three times daily. Patients in two groups were treated for 3 menstrual cycles. After treatment, the clinical efficacies were evaluated, and serum indexes, VAS scores, and cyst diameter in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 78.26% and 93.48%, respectively, and there was difference between two groups (P<0.05). After treatment, the levels of CA199, TSGF, EPO, and VEGF in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the serum indexes levels in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P<0.05). After treatment, VAS scores and cyst diameter in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the observational indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P<0.05). Conclusion Shaofu Zhuyu Granules combined with Triptorelin Acetate for injection has clinical curative effect in treatment of endometriosis, can improve clinical symptoms and signs, alleviate pain, and regulate serum indicators, which has a certain clinical application value.