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[摘要]
目的 了解西部战区总医院肾病内科住院肾性贫血患者蔗糖铁注射液的使用情况,分析评价其合理性,旨在推进临床合理用药。方法 调取西部战区总医院HIS系统中肾病内科2018年5月-2019年5月使用蔗糖铁注射液的肾性贫血患者病历资料207份,从蔗糖铁注射液的适应症、溶媒、用法用量、重复用药、禁忌症用药等方面进行合理性分析。结果 个人总用量301~600 g的患者最多,构成比为70.53%。血透患者135例,构成比为65.22%;非血透患者72例,构成比为34.78%。铁蛋白浓度≤ 100 μg/L的患者占43.96%。13例(6.28%)合并肺部感染。不合理使用情况主要为溶媒不适宜(17.87%)、用法用量不适宜(8.22%)、无适应症用药(4.83%)。结论 蔗糖铁注射液的不合理使用应引起药师和医生的重视,强化医嘱审核工作,促进用药合理性。
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[Abstract]
Objective To investigate the rational use of Iron Sucrose Injection for renal anemia in hospitalized patients in The General Hospital of Western Theater Command, so as to provide references for clinical rational medication. Methods Data of application of Iron Sucrose Injection was extracted from the HIS in The General Hospital of Western Theater Command from May 2018 to May 2019, and indications, menstruum, usage and dosage, repeated administration, and contraindication medication were retrospectively analyzed. Results Total personal consumption was mostly 301-600 g, with the constituent ratio of 70.53%. There were 135 cases of hemodialysis patients, accounting for 65.22%. There were 72 cases of nonhemodialysis patients, accounting for 65.22%. The patients with ferritin concentration ≤ 100 μg/L accounted for 43.96%. 13 Cases (6.28%) of patients had pulmonary infection. Unreasonable use of Iron Sucrose Injection mainly included unreasonable menstruum (17.87%), unreasonable usage and dosage (8.22%), and off-label drug use (4.83%). Conclusion The unreasonable use of Iron Sucrose Injection should arouse the attention of pharmacists and doctors to strengthen the review of medical advice to promote the rational of application of iron sucrose injection.
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