目的 探讨乳酸菌素片联合艽龙胶囊治疗功能性消化不良的临床效果。方法 选取选取2016年1月-2018年9月民航西安医院收治的126例功能性消化不良患者，随机分为对照组和治疗组，每组各63例。对照组口服艽龙胶囊，2粒/次，3次/d。治疗组在对照组治疗基础上口服乳酸菌素片，3片/次，3次/d，嚼服。两组均连续治疗4周。观察两组的临床疗效，比较两组治疗前后主要症状积分、餐后4、6 h的胃排空率、近端胃功能参数、NDLQI评分的变化情况。随访3个月，比较两组的复发率。结果 治疗后，对照组和治疗组的总有效率分别是84.1%、95.2%，两组比较差异具有统计学意义（P<0.05）。治疗后，两组患者治疗后各项主要症状（中上腹痛、早饱感、中上腹烧灼感、餐后饱胀不适）积分及其总分均显著降低，同组治疗前后比较差异有统计学意义（P<0.05）；治疗后，治疗组这些症候积分显著低于对照组，两组比较差异具有统计学意义（P<0.05）。治疗后，两组治疗后餐后4、6 h的胃排空率均显著增加，同组治疗前后比较差异有统计学意义（P<0.05）；治疗后，治疗组餐后4、6 h的胃排空率显著高于对照组，两组比较差异具有统计学意义（P<0.05）。治疗后，两组阈值饮水量（TV）、饱足饮水量（SV）、阈值近端胃容积（SPTV）、饱足近端胃容积（SPSV）较治疗前均显著增加，同组治疗前后比较差异有统计学意义（P<0.05）；治疗后，治疗组近端胃功能参数显著高于对照组，两组比较差异具有统计学意义（P<0.05）。治疗后，两组NDLQI中各领域（干扰、控制、食物/饮料及睡眠打扰）评分及总分较治疗前均显著增高，同组治疗前后比较差异有统计学意义（P<0.05）；治疗后，治疗组NDLQI评分显著高于对照组，两组比较差异有统计学意义（P<0.05）。随访3个月，对照组和治疗组的复发率分别是20.6%、7.9%，两组比较差异有统计学意义（P<0.05）。结论 乳酸菌素片联合艽龙胶囊治疗功能性消化不良可明显缓解患者消化不良相关症状，改善其生命质量，控制复发，具有一定的临床推广应用价值。

Objective To investigate the clinical effect of Lacidophilin Tablets combined with Jiaolong Capsules in treatment of functional dyspepsia. Methods 126 Patients with functional dyspepsia admitted to Shaanxi Civil Aviation Xi'an Hospital from January 2016 to September 2018 were randomly divided into control (n=63)and treatment groups (n=63). Patients in the control group were po administered with Jiaolong Capsules, 2 grains/time, three times daily. Patients in the treatmen group were po administered with Lacidophilin Tablets, 3 tablets/time, three times daily. Patients in two groups were treated for 4 weeks. After treatment, the clinical efficacy was evaluated, and the changes of main symptom scores, gastric emptying rates at 4 h and 6 h after meal, proximal gastric function parameters, and NDLQI scores in two groups before and after treatment were compared. Results After treatment, the clinical efficacy in the control and treatment groups were 84.1% and 95.2%, respectively, and there were differences between two groups (P<0.05). After treatment, the scores of the main symptoms (middle and upper abdominal pain, early satiety, middle and upper abdominal burning, and fullness and discomfort after meals) and total scores in the two groups were significantly reduced, and there were differences in the same group (P<0.05). After treatment, the main symptoms in the treatment group were lower than those in the control group, and there were differences between two groups (P<0.05). After treatment, the gastric emptying rates at 4 h and 6 h were significantly increased in both groups, and there were differences in the same group (P<0.05). After treatment, the gastric emptying rates at 4 h and 6 h were significantly higher than those in the control group, and there were differences between two groups (P<0.05). After treatment, TV, SV, SPTV, and SPSV were significantly increased in both groups, and there were differences in the same group (P<0.05). After treatment, the proximal gastric function parameters in the treatment group were significantly higher than those in the control group, and there were differences between two groups (P<0.05). After treatment, scores of NDLQI in all areas (interference, control, food/drink and sleep disturbance)and total scores were significantly increased in both groups, and there were differences in the same group (P<0.05). After treatment, the NDLQI scores in the treatment group were significantly higher than those in the control group, and there were differences between two groups (P<0.05). Followed up for 3 months, the recurrence rate in the control and treatment groups were 20.6% and 7.9%, respectively, and there were differences between two groups (P<0.05). Conclusion Lacidophilin Tablets combined with Jiaolong Capsules in treatment of functional dyspepsia can significantly relieved symptoms related to dyspepsia, and improve life quality, and can control recurrence, which has a certain clinical application value.