目的 了解辽宁省肿瘤医院第二类精神药品的应用现状及变化趋势，为临床合理用药提供参考。方法 收集辽宁省肿瘤医院2015-2017年第二类精神药品的应用数据，对其用量、销售金额、用药频度（DDDs）、日均药费（DDC）及药品排序比（B/A）等进行统计和分析。结果 2015-2017年，第二类精神药品的用量、销售金额逐年增长，用量排名前两位的为地佐辛注射液和地西泮片，地佐辛注射液与咪达唑仑注射液位列销售金额的前两位。第二类精神药物的DDDs逐年增长，地佐辛注射液与地西泮片的DDDs始终居前两位。地佐辛注射液、布托啡诺注射液和咪达唑仑注射液的DDC居前3位。B/A接近1.00的药品包括地佐辛注射液、酒石酸唑吡坦片。结论 辽宁省肿瘤医院第二类精神药品使用基本合理，但仍需加强监督管理，规范使用行为。

Objective To investigate the usage and variation tendency of second class psychotropic drugs in Liaoning Cancer Hospital and Institute, in order to provide reference for rational use of drugs in clinic. Methods The data of second class psychotropic drugs in Liaoning Cancer Hospital and Institute from 2015 to 2017 was collected, and the consumption quantity, consumption sum, frequency of drug use (DDDs), defined daily cost (DDC), and drug sequence ratio (B/A) were calculated and analyzed. Results From 2015 to 2017, consumption quantity and consumption sums of second class psychoactive drugs increased rapidly year by year. The top two consumption quantity of second class psychotropic drugs were Dezocine Injection and Diazepam Tablets. Consumption sum of Dezocine Injection and Midazolam Injection ranked the top two. DDDs of second class psychoactive drugs increased year by year, and DDDs of Dezocine Injection and Midazolam Injection ranked the first two persistently. DDC of Dezocine Injection, Midazolam Injection, and Butorphanol Injection ranked the top three. The second class psychotropic drugs whose B/A was close to 1.00 including Dezocine Injection and Zolpidem Tartrate Tablets. Conclusion The utilization of second class psychotropic drugs in Liaoning Cancer Hospital and Institute is basically reasonable, meanwhile, supervision should be strengthened to standardize medication behavior.