目的 分析2014-2016年中国人民解放军第一七四医院麻醉药品的使用情况，为临床合理用药提供参考。方法 对2014-2016年中国人民解放军第一七四医院麻醉药品的使用数量、用药金额及用药频度（DDDs）、日均费用（DDC）以及序号比（B/A）进行统计分析。结果 麻醉药品的使用金额逐年增加，枸橼酸芬太尼注射液的用量呈逐年下降趋势，枸橼酸舒芬太尼注射液、盐酸羟考酮控释片的用量呈逐年上升趋势。硫酸吗啡缓释片、注射用盐酸瑞芬太尼以及枸橼酸舒芬太尼注射液的使用金额一直排在前列。硫酸吗啡缓释片的DDDs一直排在前位；枸缘酸芬太尼注射液的DDDs在第1、2位间波动；枸缘酸舒芬太尼注射液则有明显的增长趋势，2016年DDDs排在第1位；芬太尼透皮贴、哌替啶注射液的DDDs基本稳定，盐酸羟考酮控释片的DDDs逐年增长。各麻醉药品3年的DDC保持稳定，注射用盐酸瑞芬太尼的DDC居首位，枸橼酸舒芬太尼注射液次之。2014年硫酸吗啡缓释片、芬太尼透皮贴、2015和2016年的吗啡片、2014-2016年磷酸可待因片的B/A均为1.00，同步性较好。结论 中国人民解放军第一七四医院麻醉药品的使用基本合理，但个别药品存在不合理现象。

Objective To analyze the utilization of narcotic drugs in No. 174 Hospital of PLA from 2014 to 2016, and provide reference for clinical rational drug use. Methods The amount, consumption sums, frequency of drug use (DDDs), defined daily cost (DDC), and drug sequence ratio (B/A) of narcotic drugs in No. 174 Hospital of PLA from 2014 to 2016 were calculated and analyzed. Results Consumption sums of narcotic drugs increased year by year. The amount of Fentanyl Citrate Injection showed a declining trend, while the amounts of Sufentanil Citrate Injection and Oxycodone Hydrochloride Controlled-release Tablets showed an upward trend year by year. Consumption sums of Morphine Sulfate Sustained-release Tablets, Remifentanil Hydrochloride for injection, and Sufentanil Citrate Injection remained at the front place. DDDs of Morphine Sulfate Sustained-release Tablets were always in the front, and DDDs of Fentanyl Citrate Injection fluctuated between the first and the second. DDDs of Sufentanil Citrate Injection showed an increasing trend, and ranked at the first place in 2016. DDDs of Fentanyl Transdermal Patches and Pethidine Hydrochloride Injection were basically stable. DDDs of Oxycodone Hydrochloride Controlled-release Tablets increased year by year. DDC of all narcotic drugs remained stable for three years. DDC of Remifentanil Hydrochloride Injection ranked the first, and Sufentanil Citrate Injection followed. B/A of Morphine Sulfate Sustained-release Tablets and Fentanyl Transdermal Patches in 2014, Morphine Tablets in 2015 and 2016, Phosphate Codeine Tablets from 2014 to 2016 were both 1.00, showing a good synchronization. Conclusion The use of the second class of psychotropic drugs in No. 174 Hospital of PLA is basically reasonable, but there are still some unreasonable use.

福建省教育厅中青年科技类项目（JAT170705）