目的 探讨十味龙胆花颗粒联合头孢曲松钠治疗老年社区获得性肺炎的临床疗效。方法 选取2016年8月-2017年8月在商丘市第五人民医院进行治疗的老年社区获得性肺炎患者92例，根据用药差别分为对照组（46例）和治疗组（46例）。对照组患者静脉滴注注射用头孢曲松钠，2 g加入生理盐水100 mL，2次/d；治疗组在对照组的基础上口服十味龙胆花颗粒，3 g/次，3次/d。两组患者均经过7 d治疗。观察两组患者临床疗效，比较治疗前后两组患者临床症状改善时间和血清学指标差异。结果 治疗后，对照组和治疗组临床有效率分别为80.43%、95.65%，两组比较差异具有统计学意义（P<0.05）。治疗后，治疗组在发热、咳痰和肺部啰音消失时间方面均显著短于对照组，两组比较差异具有统计学意义（P<0.05）。治疗后，两组血清C反应蛋白（CRP）、N端前脑钠肽（NT-proBNP）、肿瘤坏死因子-α（TNF-α）和降钙素（PCT）水平均显著降低，同组比较差异具有统计学意义（P<0.05）；且治疗组血清学指标显著低于对照组，两组比较差异具有统计学意义（P<0.05）。结论 十味龙胆花颗粒联合注射用头孢曲松钠治疗老年社区获得性肺炎疗效显著，可有效改善临床症状，降低机体炎症反应，具有一定的临床推广应用价值。

Objective To investigate the clinical efficacy of Shiwei Longdanhua Granules combined with ceftriaxone sodium in treatment of senile community acquired pneumonia. Methods Patients (92 cases) with community acquired pneumonia in Shangqiu Fifth People's Hospital from August 2016 to August 2017 were divided into control (46 cases) and treatment (46 cases) groups according to different treatments. Patients in the control group were iv administered with Ceftriaxone Sodium for injection, 2 g added into normal saline 100 mL, twice daily. Patients in the treatment group were po administered with Shiwei Longdanhua Granules on the basis of the control group, 3 g/time, three times daily. Patients in two groups were treated for 7 d. After treatment, the clinical efficacy was evaluated, and the differences of the improvement time of clinical symptom, the serological indexes in two groups before and after treatment were compared.Results After treatment, the clinical efficacy in the control and treatment groups were 80.43% and 95.65%, respectively, and there were differences between two groups (P < 0.05). After treatment, the disappearance time of fever, expectoration, and lung rale in the treatment group was significantly shorter than that in the control group, with significant difference between two groups (P < 0.05). After treatment, the CRP, NT-proBNP, TNF-α, and PCT levels in two groups were significantly decreased, and there were differences in the same group (P < 0.05), and these serological indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P < 0.05). Conclusion Shiwei Longdanhua Granules combined with ceftriaxone sodium has good effect in treatment of senile community acquired pneumonia can effectively improve the clinical symptoms and reduce the inflammatory reaction, which has a certain clinical application value.