目的 探讨银杏叶片联合盐酸法舒地尔注射液治疗冠心病慢性心力衰竭的临床疗效。方法 选取2016年6月-2017年9月凉山彝族自治州第一人民医院收治的冠心病合并慢性心力衰竭患者98例为研究对象，患者随机被分为对照组和治疗组，每组各49例。对照组静脉滴注盐酸法舒地尔注射液，30 mg加入到5%葡萄糖溶液100 mL中，2次/d，10 d为1个疗程，每个月治疗1个疗程。治疗组在对照组基础上口服银杏叶片，1片/次，3次/d。两组患者均连续治疗3个月。观察两组的临床疗效，比较两组的6 min步行距离、心功能分级、超声心动图指标、血清生化指标。结果 治疗后，对照组和治疗组的总有效率分别为77.6%、91.8%，两组比较差异具有统计学意义（P<0.05）。治疗后，两组6 min步行距离均明显增加，心功能分级均明显改善，同组治疗前后比较差异具有统计学意义（P<0.05）；且治疗组这些观察指标的改善程度明显优于对照组，两组比较差异具有统计学意义（P<0.05）。治疗后，两组左心室舒张末期内径（LVEDD）、左心室收缩末期内径（LVESD）均显著降低，左室射血分数（LVEF）、每搏量（SV）均显著升高，同组治疗前后比较差异具有统计学意义（P<0.05）；且治疗组这些观察指标的改善程度明显优于对照组，两组比较差异具有统计学意义（P<0.05）。治疗后，两组血清脑钠肽（BNP）、白细胞介素-6（IL-6）、肿瘤坏死因子-α（TNF-α）水平均显著降低，同组治疗前后比较差异具有统计学意义（P<0.05）；且治疗组这些观察指标明显低于对照组，两组比较差异具有统计学意义（P<0.05）。结论 银杏叶片联合盐酸法舒地尔注射液治疗冠心病慢性心力衰竭具有较好的临床疗效，可改善患者的心功能，降低炎性指标，提高运动能力，安全性较好，具有一定的临床推广应用价值。

Objective To investigate the clinical effects of Yinxingye Tablets combined with Fasudil Hydrochloride Injection in treatment of chronic heart failure of coronary heart disease. Methods Patients (92 cases) with chronic heart failure of coronary heart disease in the First People's Hospital of Liangshan Yi Autonomous Prefecture from June 2016 to September 2017 were randomly divided into control and treatment groups, and each group had 49 cases. Patients in the control group were iv administered with Fasudil Hydrochloride Injection, 30 mg added into 5% glucose solution 100 mL, twice daily, 10 d/course, 1 course/month. Patients in the treatment group were po administered with Yinxingye Tablets on the basis of the control group, 1 tablet/time, three times daily. Patients in two groups were treated for 3 months. After treatment, the clinical efficacies were evaluated, and 6 min walking distance, cardiac function classification, echocardiographic indexes, and serum biochemical indexes in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 77.6% and 91.8%, respectively, and there was difference between two groups (P < 0.05). After treatment, the 6 min walking distance in two groups were significantly increased, and cardiac function classifications in two groups were significantly improved, and the difference was statistically significant in the same group (P < 0.05). And the observational indexes in the treatment group were significantly better than those in the control group, with significant difference between two groups (P < 0.05). After treatment, LVEDD and LVESD in two groups were significantly decreased, but LVEF and SV in two groups were significantly decreased, and the difference was statistically significant in the same group (P < 0.05). And the observational indexes in the treatment group were significantly better than those in the control group, with significant difference between two groups (P < 0.05). After treatment, the levels of BNP, IL-6, and TNF-α in two groups were significantly decreased, and the difference was statistically significant in the same group (P < 0.05). And the observational indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P < 0.05). Conclusion Yinxingye Tablets combined with Fasudil Hydrochloride Injection has clinical curative effect in treatment of chronic heart failure of coronary heart disease, can improve the heart function, decrease the inflammatory index, and improve exercise ability, with good safety, which has a certain clinical application value.