目的 观察丹红注射液联合氟桂利嗪治疗椎基底动脉供血不足眩晕的临床疗效。方法 选取2016年2月-2017年2月在黄石市中心医院就诊的椎基底动脉供血不足眩晕患者96例，随机分为对照组和治疗组，每组各48例。对照组患者睡前口服盐酸氟桂利嗪胶囊，5 mg/次，1次/d；治疗组在对照组的基础上静脉滴注丹红注射液，30 mL加入5%葡萄糖注射250 mL中，1次/d。两组患者均治疗14 d。评价两组患者临床疗效，同时比较治疗前后两组患者三酰甘油（TG）、胆固醇（TC）、高切全血黏度、低切全血黏度、椎基底动脉最大血流速度和临床症状改善情况。结果 治疗后，对照组和治疗组的总有效率分别为83.33%、91.67%，两组比较差异具有统计学意义（P<0.05）。治疗后，两组TG、TC、高切全血黏度和低切全血黏度指标水平均显著下降（P<0.05）；且治疗组患者上述指标明显低于对照组（P<0.05）。治疗后，两组患者椎基底动脉最大血流速度均明显增加（P<0.05）；且治疗组患者椎基底动脉最大血流速度明显高于对照组（P<0.05）。治疗后，两组患者眩晕积分均明显改善（P<0.05）；且治疗组患者眩晕积分明显低于对照组（P<0.05）。结论 丹红注射液联合氟桂利嗪治疗椎基底动脉供血不足性眩晕临床疗效确切，不良反应较轻，具有一定的临床推广应用价值。

Objective To observe the clinical curative effect of Danhong Injection combined with flunarizine in treatment of vertebrobasilar insufficiency vertigo. Methods Patients (96 cases) with vertebrobasilar insufficiency vertigo in Huangshi Central Hospital from February 2016 to February 2017 were randomly divided into control and treatment groups, and each group had 48 cases. Patients in the control group were po administered with Flunarizine Hydrochloride Capsules, 5 mg/time, once daily. Patients in the treatment group were iv administered with Danhong Injection on the basis of the control group, 30 mL added into 5% glucose injection 250 mL, once daily. Patients in two groups were treated for 14 d. After treatment, the clinical efficacy was evaluated, and the improvement of TG, TC, high blood viscosity, low shear blood viscosity, maximum blood flow velocity of vertebrobasilar artery and clinical symptoms in two groups before and after treatment were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 83.33% and 91.67%, respectively, and there was difference between two groups (P<0.05). After treatment, the TG, TC, high blood viscosity, and low shear blood viscosity in two groups were significantly decreased (P<0.05). And these indexes in the treatment group were obviously better than those in the control group (P<0.05). After treatment, the maximum blood flow velocity of vertebrobasilar artery in two groups were significantly increased (P<0.05). And the velocity in the treatment group was obviously higher than that in the control group (P<0.05). After treatment, the vertigo symptom score in two groups were significantly improved (P<0.05). And the vertigo symptom score in the treatment group was significantly lower than that in the control group (P<0.05). Conclusion Danhong Injection combined with flunarizine has good clinical curative effect in treatment of vertebrobasilar insufficiency vertigo with less adverse reactions, which has a certain clinical application value.