目的 观察妇科再造胶囊联合炔诺酮治疗无排卵型功能性子宫出血的临床疗效。方法 选取2015年7月—2016年6月在监利县人民医院就诊的无排卵型功能性子宫出血患者106例，随机分为对照组和治疗组，每组各53例。对照组口服复方炔诺酮片，5 mg/次，1次/8 h，血止后逐渐调整为2.5 mg/次维持，自血止日算起，连服22 d。1个月经周期为1个疗程，停药后待月经来潮第5天开始进行下一周期治疗。治疗组在对照组的基础上于经前1周开始口服妇科再造胶囊，10粒/次，2次/d。1个月经周期为1个疗程。两组患者均治疗3个疗程。评价治疗后两组患者临床疗效，同时比较治疗前后两组临床改善情况以及雌激素（E₂）、孕酮（P）和血红蛋白（Hb）水平变化。结果 治疗后，对照组和治疗组总有效率分别为75.47%和90.57%，两组比较差异具有统计学意义（P< 0.05）。治疗后，两组患者月经周期和经期时间均显著趋于正常范围，子宫内膜厚度也明显改善，同组治疗前后比较差异具有统计学意义（P< 0.05）；且治疗组临床改善情况明显好于对照组，两组比较差异具有统计学意义（P< 0.05）。治疗后，两组患者E₂和P均显著降低，Hb水平明显升高，同组比较差异具有统计学意义（P< 0.05）；且治疗组E₂、P和Hb水平显著优于对照组，两组比较差异具有统计学意义（P< 0.05）。结论 妇科再造胶囊联合炔诺酮治疗功能性子宫出血临床疗效确切，症状体征明显改善，具有一定的临床推广应用价值。

Objective To observe the clinical efficacy of Fuke Zaizao Capsules combined with norethindrone in treatment of anovulatory dysfunctional uterine bleeding. Methods Patients (106 cases) with anovulatory dysfunctional uterine bleeding in Jianli People's Hospital from July 2015 to June 2016 were randomly divided into control and treatment groups, and each group had 53 cases. Patients in the control group were po administered with Compound Norethisterone Tablets, 5 mg/time, once every 8 h, and the dosage was adjusted to 2.5 mg/time gradually after blood stopped, they were treated for 22 d from the day of the bleeding stopped. One menstrual cycle was as one course of treatment. After stopping the drugs, the next treatment cycle begined after the fifth day of menstruation. Patients in the treatment group were po administered with Fuke Zaizao Capsules 1 week before menstruation on the basis of the control group, 10 grains/time, twice daily. One menstrual cycle was as one course of treatment. Patients in two groups were treated for 3 courses. After treatment, clinical efficacy was evaluated, and the clinical improvement, the changes of E₂, P, and Hb levels in two groups before and after treatment were compared. Results After treatment, the clinical efficacy in the control and treatment groups were 75.47% and 90.57%, respectively, and there were differences between two groups (P < 0.05). After treatment, the menstrual cycle and menstrual period in two groups significantly tended to normal range, endometrial thickness were also significantly improved, and the difference was statistically significant in the same group (P < 0.05). And the clinical improvement in the treatment group was significantly better than that in the control group, with significant difference between two groups (P < 0.05). After treatment, the E₂ and P levels in two groups were significantly decreased, Hb level was significantly increased, and there were differences in the same group (P < 0.05). And the E₂, P, and Hb levels in treatment group were significantly better than those in the control group, with significant difference between two groups (P < 0.05). Conclusion Fuke Zaizao Capsules combined with norethindrone has definite clinical efficacy in treatment of anovulatory dysfunctional uterine bleeding with obvious improvement of symptoms and signs, which has a certain clinical application value.