目的 探讨注射用磷酸肌酸钠联合注射用丹参多酚酸盐治疗冠心病心绞痛的临床疗效。方法 选取2014年9月-2016年9月聊城市第三人民医院收治的冠心病心绞痛患者181例，随机分为对照组（90例）和治疗组（91例）。对照组静脉滴注注射用丹参多酚酸盐，200 mg加入到5%葡萄糖注射液250 mL中，1次/d。治疗组在对照组基础上静脉滴注注射用磷酸肌酸钠，1.0 g加入到5%葡萄糖注射液250 mL中，2次/d。两组患者均连续治疗2周。观察两组的临床疗效，比较两组的超声心动图指标和安全性。结果 治疗后，对照组和治疗组的总有效率分别为83.33%、95.60%，两组比较差异有统计学意义（P<0.05）。治疗后，两组左心室舒张末期内径（LVEDD）、左心室收缩末期内径（LVESD）和左房舒张末期内径（LADD）均显著下降，而左室射血分数（LVEF）均显著下降，同组治疗前后比较差异有统计学意义（P<0.05）；且治疗组这些观察指标的改善程度明显优于对照组，两组比较差异具有统计学意义（P<0.05）。结论 注射用磷酸肌酸钠联合注射用丹参多酚酸盐治疗冠心病心绞痛具有较好的临床疗效，可改善心功能，安全性好，具有一定的临床推广应用价值。

Objective To evaluate the effect of Creatine Phosphate Sodium for injection combined with Tanshinpolyphenolic Salt for injection in treatment of angina pectoris of coronary heart disease. Methods Patients (181 cases) with angina pectoris of coronary heart disease in Liaocheng Third People's Hospital from September 2014 to September 2016 were randomly divided into the control group (90 cases) and the treatment group (91 cases). Patients in the control group were iv administered with Tanshinpolyphenolic Salt for injection, 200 mg added into 5% glucose solution 250 mL, once daily. Patients in the treatment group were iv administered with Creatine Phosphate Sodium for injection on the basis of the control group, 1.0 g added into 5% glucose solution 250 mL, once daily. Patients in two groups were treated for 2 weeks. After treatment, the clinical efficacies were evaluated, and echocardiographic indexes and safety in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 83.33% and 95.60%, respectively, and there was difference between two groups (P<0.05). After treatment, LVEDD, LVESD, and LADD in two groups were significantly decreased, but the LVEF in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the observational indexes in the treatment group were significantly better than those in the control group, with significant difference between two groups (P<0.05). Conclusion Creatine Phosphate Sodium for injection combined with Tanshinpolyphenolic Salt for injection has clinical curative effect in treatment of angina pectoris of coronary heart disease, can improve heart function with safety, which has a certain clinical application value.