目的 探讨复方伸筋胶囊联合依托考昔治疗痛风的临床疗效。方法 选取2015年6月-2016年6月在贵阳中医学院第二附属医院进行治疗的痛风患者82例，根据治疗方案的差别分为对照组（41例）和治疗组（41例）。对照组口服依托考昔片，1片/次，1次/d。治疗组在对照组的基础上口服复方伸筋胶囊，4粒/次，3次/d。两组患者均连续治疗7 d。治疗后，比较两组患者的临床疗效，并对治疗前后两组临床症状评分、血清炎性因子和血清黄嘌呤氧化酶（XOD）和血尿酸（UA）水平进行比较。结果 治疗后，对照组和治疗组的总有效率分别为80.49%、95.12%，两组比较差异具有统计学意义（P<0.05）。两组患者临床症状评分均较同组治疗前显著降低（P<0.05），且治疗组上述评分降低的更明显（P<0.05）；两组患者血清CRP、IL-1β、IL-6和TNF-α水平均显著降低，同组治疗前后比较差异具有统计学意义（P<0.05）；且治疗组血清炎性因子水平优于对照组，两组比较差异具有统计学意义（P<0.05）。两组血清XOD、UA水平均较同组治疗前显著降低（P<0.05），且治疗组上述指标降低的更明显，两组比较差异具有统计学意义（P<0.05）。结论 复方伸筋胶囊联合依托考昔治疗痛风效果显著，有利于改善临床症状，明显降低机体炎性反应和XOD、UA水平，具有一定的临床推广应用价值。

Objective To explore the clinical effect of Fufang Shenjin Capsules combined with etoricoxib in treatment of gout. Methods Patients (82 cases) with gout in No. 2 Hospital Affiliated to TCM College of Guiyang from June 2015 to June 2016 were divided into control group (41 cases) and treatment group (41 cases) according to the different treatments. Patients in the control group were po administered with Etoricoxib Tablets, 1 tablets/time, once daily. Patients in the treatment group were po administered with Fufang Shenjin Capsules on the basis of the control group, 4 grains/time, three times daily. The patients in two groups were treated for 7 d. After treatment, the clinical efficacies were evaluated, clinical symptom scores, serum inflammatory factors, XOD and UA levels in serum before and after treatment in two groups were compared. Results After treatment, the total efficacies in the control and treatment groups were 80.49% and 95.12%, respectively, and there were differences between two groups (P<0.05). Clinical symptom scores in two groups were significantly decreased compared with those before treatment in the same group (P<0.05). And the scores in the treatment group were decreased more than those in the control group with significant difference between two groups (P<0.05). CRP, IL-1β, IL-6, and TNF-α levels in serum were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the decreasing degree in the treatment group was obviously better than that in the control group, with significant difference between two groups (P<0.05). XOD and UA levels in serum were significantly decreased (P<0.05). And these indexes in the treatment group were significantly decreased with significant difference between two groups (P<0.05). Conclusion Fufang Shenjin Capsules combined with etoricoxib has clinical curative effect in treatment of gout, and can improve clinical symptoms and significantly reduce the inflammatory reaction and XOD and UA levels, which has a certain clinical application value.